ArticleNature genetics2017
Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis.
Article in Nature genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers.
What it found
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Who cites it
160 citing papers in PubMed, 298 citations in OpenAlex.
- Epigenetic maintenance of PRC2-repressed chromatin requires RTT109 but not H3K56 acetylation.PLoS genetics · 2026Article
- DNA methylation either antagonizes or promotes Polycomb recruitment at transposable elements in Arabidopsis.Nature communications · 2026Article
- Atypical E2F transcription factors couple Polycomb Repressive Complex 2 to endosperm cell division and differentiation.Nature plants · 2026Article
- Molecular integration of seasonal temperature signals in flowering time control.Nature reviews. Genetics · 2026Review
- Epigenetically regulated transcriptional repressor, BASIC PENTACYSTEINE1 (BPC1) acts together with polycomb repressive complex 2 (PRC2) to suppress camalexin biosynthesis in Arabidopsis.Plant molecular biology · 2026Article
- Histone deacetylases and cell-cycle regulators orchestrate cell-identity transitions during Arabidopsis root regeneration.Molecular plant · 2026Article
- Graded versus ON/OFF control in quantitative gene expression and epigenetic memory.The EMBO journal · 2026Review
- Chromatin accessibility landscape and its association with heterosis in maize hybrids.Nature communications · 2026Article
- CUT&Tag for High-Resolution Epigenomic Profiling From a Low Amount ofPlant direct · 2026Article
- Epigenetic gene regulation is controlled by distinct regulatory complexes utilizing specialized paralogs of TELOMERE REPEAT BINDING FACTORS.PLoS genetics · 2026Article
- EMF2b-1 regulates endosperm cell cycling through PRC2 recruitment in maize.Genome biology · 2026Article
- Finding balance: the dynamic interplay between H3K27me3 writers and erasers in regulating environmental plasticity and memory.The New phytologist · 2026Review
- 3D epigenome architecture orchestrates cis and trans regulation of flowering time in rice.Genome biology · 2026Article
- ZINC FINGER PROTEIN 1 and 8 interact with polycomb repressive complex 2 to repress class B and C floral organ identity genes.Nucleic acids research · 2026Article
- Antagonistic regulation of anthocyanin biosynthesis by HY5 and BPC1 inFrontiers in plant science · 2026Article
- Transcription factor-mediated recruitment of small interfering RNA production.Nature plants · 2025Article
- PKL mediates H3K4me2 modification and spatial gene congregation in chromatin regulation.Nucleic acids research · 2025Article
- PRC1-mediated H2A.Zub promotes gene expression by preventing H3.1K27me1 incorporation in Arabidopsis.Genome biology · 2025Article
- Precise control of chromatin loop extrusion enhances sustainable green revolution yield in rice.Nature genetics · 2025Article
- Plant mobile domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression.Nature plants · 2025Article
100 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors at 8 institutions in 5 countries.
Funding
Abstract
Disruption of gene silencing by Polycomb protein complexes leads to homeotic transformations and altered developmental-phase identity in plants. Here we define short genomic fragments, known as Polycomb response elements (PREs), that direct Polycomb repressive complex 2 (PRC2) placement at developmental genes regulated by silencing in Arabidopsis thaliana. We identify transcription factor families that bind to these PREs, colocalize with PRC2 on chromatin, physically interact with and recruit PRC2, and are required for PRC2-mediated gene silencing in vivo. Two of the cis sequence motifs enriched in the PREs are cognate binding sites for the identified transcription factors and are necessary and sufficient for PRE activity. Thus PRC2 recruitment in Arabidopsis relies in large part on binding of trans-acting factors to cis-localized DNA sequence motifs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.