Evidence map›Paper›PMID 28825682›Full record

ReviewMaterials (Basel, Switzerland)2017

Potential Applications of Nanocellulose-Containing Materials in the Biomedical Field.

Nadia Halib, Francesca Perrone, Maja Cemazar, Barbara Dapas, Rossella Farra, Michela Abrami, Gianluca Chiarappa, Giancarlo Forte, Fabrizio Zanconati, Gabriele Pozzato and 6 more

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 171 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A Simple and Cost-Effective FeClACS applied materials & interfaces · 2024
    Article
  5. Three-Dimensional Printed Cellulose for Wound Dressing Applications.3D printing and additive manufacturing · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Porphyrin Photosensitizers Grafted in Cellulose Supports: A Review.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Review
  13. Controlled release of vitamin DScientific reports · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 4 countries.

Nadia HalibDepartment of Basic Sciences & Oral Biology, Faculty of Dentistry, Universiti Sains Islam Malaysia, Level 15, Tower B, Persiaran MPAJ, Jalan Pandan Utama, Kuala Lumpur 55100, Malaysia;. nadia.halib@usim.edu.my.
Francesca PerroneDepartment of Life Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149 Trieste, Italy. fperrone116@gmail.com.
Maja CemazarInstitute of Oncology Ljubljana, Zaloska 2, SI-1000 Ljubljana, Slovenia. MCemazar@onko-i.si.
Barbara DapasDepartment of Life Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149 Trieste, Italy. bdapas@units.it.
Rossella FarraDepartment of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127 Trieste, Italy. rfarra@units.it.
Michela AbramiDepartment of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127 Trieste, Italy. mikystars@hotmail.com.
Gianluca ChiarappaDepartment of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127 Trieste, Italy. gianluca.chiarappa@phd.units.it.
Giancarlo ForteCenter for Translational Medicine, International Clinical Research Center, St. Anne's University Hospital, Pekarska 53, 656 91 Brno, Czech Republic. giaforte@gmail.com.
Fabrizio ZanconatiSurgery and Health Sciences, Department of Medical, Cattinara Hospital, University of Trieste, I-34127 Trieste, Italy. fabrizio.zanconati@asuits.sanita.fvg.it.
Gabriele PozzatoSurgery and Health Sciences, Department of Medical, Cattinara Hospital, University of Trieste, I-34127 Trieste, Italy. G.POZZATO@fmc.units.it.
Luigi MurenaSurgery and Health Sciences, Department of Medical, Cattinara Hospital, University of Trieste, I-34127 Trieste, Italy. lmurena@units.it.
Nicola FiottiSurgery and Health Sciences, Department of Medical, Cattinara Hospital, University of Trieste, I-34127 Trieste, Italy. fiotti@units.it.
Romano LapasinDepartment of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127 Trieste, Italy. romano.lapasin@dia.units.it.
Laura CansolinoDepartment of Clinico-Surgical Sciences, Experimental Surgery Laboratory, University of Pavia and IRCCS S, Matteo Hospital Pavia, 27100 Pavia, Italy. lauracansolino@libero.it.
Gabriele GrassiDepartment of Life Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149 Trieste, Italy. ggrassi@units.it.
Mario GrassiDepartment of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127 Trieste, Italy. mario.grassi@dia.units.it.
University of Trieste · ITOspedale di Cattinara · ITInstitute of Oncology Ljubljana · SISt. Anne's University Hospital Brno · CZUniversiti Sains Islam Malaysia · MYUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because of its high biocompatibility, bio-degradability, low-cost and easy availability, cellulose finds application in disparate areas of research. Here we focus our attention on the most recent and attractive potential applications of cellulose in the biomedical field. We first describe the chemical/structural composition of cellulose fibers, the cellulose sources/features and cellulose chemical modifications employed to improve its properties. We then move to the description of cellulose potential applications in biomedicine. In this field, cellulose is most considered in recent research in the form of nano-sized particle, i.e., nanofiber cellulose (NFC) or cellulose nanocrystal (CNC). NFC is obtained from cellulose via chemical and mechanical methods. CNC can be obtained from macroscopic or microscopic forms of cellulose following strong acid hydrolysis. NFC and CNC are used for several reasons including the mechanical properties, the extended surface area and the low toxicity. Here we present some potential applications of nano-sized cellulose in the fields of wound healing, bone-cartilage regeneration, dental application and different human diseases including cancer. To witness the close proximity of nano-sized cellulose to the practical biomedical use, examples of recent clinical trials are also reported. Altogether, the described examples strongly support the enormous application potential of nano-sized cellulose in the biomedical field.

Indexed as

bone-cartilage regenerationcellulosedental applicationdrug-cell deliverysiRNAwound healing

Identifiers

PMID28825682
PMCPMC5578343
OpenAlexW2746198675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.