Evidence map›Paper›PMID 28825642›Full record

ReviewNutrients2017

Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity.

María Herranz-López, Mariló Olivares-Vicente, José Antonio Encinar, Enrique Barrajón-Catalán, Antonio Segura-Carretero, Jorge Joven, Vicente Micol

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 80 citations in OpenAlex.

  1. Trial
  2. Current computer-aided drug design · 2024
    Article
  3. The Multitarget Action of Vitamins in the Ischemic Stroke.Current topics in medicinal chemistry · 2024
    Review
  4. Effect of the Combination ofFoods (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Foods (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Article
  10. Phytochemical Analysis, Antioxidant, Antimicrobial, and Anti-Swarming Properties ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  11. Review
  12. Metabolic and Epigenetics Action Mechanisms of Antiobesity Medicinal Plants and Phytochemicals.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  13. Comprehensive Analysis of Antioxidant Compounds fromAntioxidants (Basel, Switzerland) · 2020
    Article
  14. Article
  15. Article
  16. Organic Acids from Roselle (Biomedicines · 2020
    Review
  17. Article
  18. Review
  19. Article
  20. Beneficial Effects of Natural Bioactive Compounds fromMolecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

María Herranz-LópezInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Edificio Torregaitán, Elche 03202, Spain. mherranz@umh.es.
Mariló Olivares-VicenteInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Edificio Torregaitán, Elche 03202, Spain. maria.olivares@umh.es.
José Antonio EncinarInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Edificio Torregaitán, Elche 03202, Spain. jant.encinar@umh.es.
Enrique Barrajón-CatalánInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Edificio Torregaitán, Elche 03202, Spain. e.barrajon@umh.es.
Antonio Segura-CarreteroDepartment of Analytical Chemistry, University of Granada, Avda. Fuentenueva s/n, Granada 18071, Spain. ansegura@ugr.es.
Jorge JovenUnitat de Recerca Biomèdica, Hospital Universitari Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus 43201, Spain. jjoven@grupsagessa.com.
Vicente MicolInstituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández (UMH), Edificio Torregaitán, Elche 03202, Spain. vmicol@umh.es.
Universitat de Miguel Hernández d'Elx · ESInstitut de Recerca Biomèdica Catalunya Sud · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Improper diet can alter gene expression by breaking the energy balance equation and changing metabolic and oxidative stress biomarkers, which can result in the development of obesity-related metabolic disorders. The pleiotropic effects of dietary plant polyphenols are capable of counteracting by modulating different key molecular targets at the cell, as well as through epigenetic modifications.

Indexed as

AnimalsAntioxidantsDisease Models, AnimalEpigenesis, GeneticHibiscusHumansObesityOxidative StressPhytotherapyPlant ExtractsPolyphenolsTissue DistributionAntioxidantsPlant ExtractsPolyphenolsantioxidantsdietary supplementationepigeneticsHibiscus sabdariffametabolic stressmetabolitesobesitypolyphenolsvirtual screening

Identifiers

PMID28825642
PMCPMC5579700
OpenAlexW2746129250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.