Evidence map›Paper›PMID 28825457›Full record

ArticleACS applied materials & interfaces2017

Screening Platform for Cell Contact Guidance Based on Inorganic Biomaterial Micro/nanotopographical Gradients.

Qihui Zhou, Olga Castañeda Ocampo, Carlos F Guimarães, Philipp T Kühn, Theo G van Kooten, Patrick van Rijn

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qihui ZhouDepartment of Biomedical Engineering-FB40, University of Groningen, University Medical Center Groningen , Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.ORCID http://orcid.org/0000-0003-2474-4197
Olga Castañeda OcampoZernike Institute for Advanced Materials, University of Groningen , Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Carlos F GuimarãesDepartment of Biomedical Engineering-FB40, University of Groningen, University Medical Center Groningen , Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Philipp T KühnDepartment of Biomedical Engineering-FB40, University of Groningen, University Medical Center Groningen , Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Theo G van KootenDepartment of Biomedical Engineering-FB40, University of Groningen, University Medical Center Groningen , Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.
Patrick van RijnDepartment of Biomedical Engineering-FB40, University of Groningen, University Medical Center Groningen , Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-2208-5725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput screening (HTS) methods based on topography gradients or arrays have been extensively used to investigate cell-material interactions. However, it is a huge technological challenge to cost efficiently prepare topographical gradients of inorganic biomaterials due to their inherent material properties. Here, we developed a novel strategy translating PDMS-based wrinkled topography gradients with amplitudes from 49 to 2561 nm and wavelengths between 464 and 7121 nm to inorganic biomaterials (SiO

Indexed as

Biocompatible MaterialsCell AdhesionFocal AdhesionsHumansMesenchymal Stem CellsNanostructuresSilicon DioxideSurface PropertiesBiocompatible MaterialsSilicon Dioxidebiomimetic surfacehigh-throughput screeninginorganic biomaterialsstem cell behaviortopographical gradient

Identifiers

PMID28825457
PMCPMC5609122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.