Evidence map›Paper›PMID 28825314›Full record

SynthesisCephalalgia : an international journal of headache2018

Perceived triggers of primary headache disorders: A meta-analysis.

A Brooke Walters Pellegrino, Rachel E Davis-Martin, Timothy T Houle, Dana P Turner, Todd A Smitherman

Open access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Cephalalgia : an international journal of headache, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 6 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 6 syntheses or guidelines pooled it, 312 citations in OpenAlex.

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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

A Brooke Walters Pellegrino1 3759 Hartford HealthCare Headache Center , West Hartford, CT, USA.
Rachel E Davis-Martin2 University of Massachusetts Medical School, Department of Emergency Medicine, Worcester, MA, USA.
Timothy T Houle3 2348 Massachusetts General Hospital , Department of Anesthesia, Critical Care, and Pain Medicine, Boston, MA, USA.
Dana P Turner3 2348 Massachusetts General Hospital , Department of Anesthesia, Critical Care, and Pain Medicine, Boston, MA, USA.
Todd A Smitherman4 University of Mississippi, Department of Psychology, University, MS, USA.
Massachusetts General Hospital · USHartford Hospital · USUniversity of Massachusetts Chan Medical School · USUniversity of Mississippi · US

Funding

Physiological Arousal and HeadacheR01NS065257 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOULE, TIMOTHY T · 2009 to 2018
$3.4M
NINDS NIH HHS R01 NS065257
6 · The paper itself

Abstract

Objective To quantitatively synthesize extant literature on perceived triggers of primary headache disorders. Methods A meta-analytic review of headache trigger survey studies was conducted. Endorsement rates, assessment method, and headache and sample characteristics were extracted from included articles. Separate random-effects models were used to assess trigger endorsement rates and post-hoc meta-regressions examined potential moderator variables. Results 85 articles from 1958 to 2015 were included, involving 27,122 participants and querying 420 unique triggers (collapsed into 15 categories). Four-fifths (0.81; 95% CI .75 to .86) of individuals with migraine or tension-type headache endorsed at least one trigger. Rates increased with the number of categories queried (OR: 1.18, 1.08-1.30) and year of publication (OR: 1.04, 1.00-1.08). The triggers most commonly endorsed were stress (.58, .53-.63) and sleep (.41, .36-.47). Conclusions Extreme heterogeneity characterizes the headache trigger literature. Most individuals with a primary headache disorder perceive their attacks to be triggered by one or more precipitants, the most common of which are stress and sleep. However, trigger endorsement is influenced by method of assessment. Enhancing methodological consistency and prioritizing experimental studies would improve our understanding of headache triggers.

Indexed as

Headache Disorders, PrimaryHumansHeadache triggersmigrainetension-type headache

Identifiers

PMID28825314
PMCPMC8544028
OpenAlexW2746815301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.