Evidence map›Paper›PMID 28825212›Full record

ArticleInfection2017

Peritonitis in a neonate due to Cyberlindnera fabianii, an ascomycetic yeast.

H Hof, V Amann, C Tauber, A Paulun

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Central line-associatedQatar medical journal · 2025
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  2. Foods (Basel, Switzerland) · 2024
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  4. The Flo Adhesin Family.Pathogens (Basel, Switzerland) · 2021
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  10. Spectrum and management of rareTherapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

H HofMVZ Labor Limbach, Im Breitspiel 16, 69126, Heidelberg, Germany. herbert.hof@labor-limbach.de.
V AmannPaediatric Cardiac Intensive Care Unit, German Paediatric Heart Center, Asklepios Klinik St. Augustin GmbH, Arnold-Janssen Str. 29, 53757, Sankt Augustin, Germany.
C TauberMVZ Labor Limbach, Im Breitspiel 16, 69126, Heidelberg, Germany.
A PaulunPaediatric Cardiac Intensive Care Unit, German Paediatric Heart Center, Asklepios Klinik St. Augustin GmbH, Arnold-Janssen Str. 29, 53757, Sankt Augustin, Germany.
Asklepios Klinik Sankt Augustin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ascomycetous yeast Cyberlindera fabianii is not only present in the environment, but is also occasionally pathogenic. Especially, neonates seem to be prone to infection. Here, we describe a case of peritoneal infection of a neonate after congenital heart surgery. The correct identification of this peculiar species is made by MALDI-TOF and especially by molecular biology methods, whereas the standard biochemical identification methods fail.The neonate with a hypoplastic left heart syndrome had a Norwood palliation followed by transient ECMO therapy for 3 days. The patient developed a renal insufficiency, so that peritoneal dialysis was initiated. After a few days, a peritoneal infection due to C. fabianii emerged. The proper source of this rare and particular yeast remains obscure. In spite of a reasonable antimycotic therapy, the patient developed a capillary leak syndrome and died finally in septic shock with multiorgan failure. One reason is probably that the yeast population, which was highly susceptible to all common antimycotic drugs at the beginning of therapy with fluconazole (and for a short period with caspofungin and liposomal amphotericin B), became rapidly resistant.

Indexed as

CandidaCandidiasisCardiac Surgical ProceduresDrug Resistance, Multiple, FungalFatal OutcomeFemaleHumansInfant, NewbornMultiple Organ FailurePeritonitisPostoperative ComplicationsSaccharomycetalesCyberlindneraMALDI-TOFNeonatePeritoneal infection

Identifiers

PMID28825212
OpenAlexW2747036337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.