Evidence map›Paper›PMID 28825176›Full record

ArticleEndocrine2017

The dual role of group V secretory phospholipase A

Preetha Shridas, Victoria P Noffsinger, Andrea C Trumbauer, Nancy R Webb

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The Phospholipase AJournal of lipid and atherosclerosis · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Harmful and protective roles of group V phospholipase ABiochimica et biophysica acta. Molecular and cell biology of lipids · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Preetha ShridasSaha Cardiovascular Research Center, University of Kentucky Medical Center, Lexington, KY, 40536, USA. pshri2@uky.edu.ORCID http://orcid.org/0000-0002-2532-4007
Victoria P NoffsingerSaha Cardiovascular Research Center, University of Kentucky Medical Center, Lexington, KY, 40536, USA.
Andrea C TrumbauerSaha Cardiovascular Research Center, University of Kentucky Medical Center, Lexington, KY, 40536, USA.
Nancy R WebbSaha Cardiovascular Research Center, University of Kentucky Medical Center, Lexington, KY, 40536, USA.
University of Kentucky · US

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2012 to 2017
$13.7M
Group X sPLA2: Regulator of Lipolysis and Glucose HomeostasisR01DK082419 · NIDDK · UNIVERSITY OF KENTUCKY · PI WEBB, NANCY R · 2009 to 2013
$1.6M
National Heart, Lung, and Blood Institute R01 DK082419National Institute of General Medical Sciences P20 GM103527NIDDK NIH HHS R01 DK082419NIGMS NIH HHS P20 GM103527
6 · The paper itself

Abstract

purposeGroup X (GX) and group V (GV) secretory phospholipase A

methodsGSIS and pancreatic islet-size were assessed in wild-type (WT) and GV sPLA

resultsGSIS was significantly decreased in islets isolated from GV KO mice compared to WT mice and in MIN6 cells with siRNA-mediated GV sPLA

conclusionsDeficiency of GV sPLA

Indexed as

AnimalsArachidonic AcidCell LineCell ProliferationDinoprostoneGlucoseGlucose Tolerance TestGroup V Phospholipases A2InsulinInsulin-Secreting CellsInsulin SecretionIslets of LangerhansMiceMice, Inbred C57BLMice, KnockoutRNA-Induced Silencing ComplexArachidonic AcidDinoprostoneGlucoseGroup V Phospholipases A2InsulinRNA-Induced Silencing ComplexArachidonic acidGV sPLA2Insulin secretionType 2 diabetesβ-islet mass

Identifiers

PMID28825176
PMCPMC5693688
OpenAlexW2747939195

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.