Evidence map›Paper›PMID 28825137›Full record

ArticleParasitology research2017

Anti-CD25 monoclonal antibody enhances the protective efficacy of Schistosoma japonicum GST vaccine via inhibition of CD4

Chun-Lian Tang, Jin Yang, Liang-Yu Cheng, Lan-Fang Cheng, Zhi-Ming Liu

Abstract read
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In one paragraph

Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Clinical & translational immunology · 2024
    Review
  2. Transmission-Blocking Vaccines against Schistosomiasis Japonica.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Journal of immunology research · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chun-Lian TangDepartment of Clinical Laboratory, Wuchang Hospital, No. 116 Yangyuan Street, Wuhan, 430063, China.
Jin YangDepartment of Clinical Laboratory, Wuchang Hospital, No. 116 Yangyuan Street, Wuhan, 430063, China.
Liang-Yu ChengDepartment of Clinical Laboratory, Wuchang Hospital, No. 116 Yangyuan Street, Wuhan, 430063, China.
Lan-Fang ChengDepartment of Clinical Laboratory, Wuchang Hospital, No. 116 Yangyuan Street, Wuhan, 430063, China.
Zhi-Ming LiuDepartment of Clinical Laboratory, Wuchang Hospital, No. 116 Yangyuan Street, Wuhan, 430063, China. m13419550695@163.com.
Wuchang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of anti-CD25 monoclonal antibody (anti-CD25 mAb) on the protection efficacy of Schistosoma japonicum 26 kDa GST (glutathione-S-transferase) vaccine was evaluated. Mice were immunized with GST before infection with S. japonicum cercariae and then injected with anti-CD25 mAb. The worm reduction rate was promoted from 24.18% in mice with GST immunization to 47.09% in mice with GST plus anti-CD25 mAb. Compared with the control group, the percentages of splenic CD4

Indexed as

AnimalsAntibodies, MonoclonalFemaleGlutathione TransferaseHelminth ProteinsHumansImmunizationInterleukin-2Interleukin-2 Receptor alpha SubunitMiceMice, Inbred BALB CSchistosoma japonicumSchistosomiasis japonicaSpleenT-Lymphocytes, RegulatoryVaccinationAntibodies, MonoclonalGlutathione TransferaseHelminth ProteinsInterleukin-2Interleukin-2 Receptor alpha SubunitVaccinesAnti-CD25 mAbCD4+CD25+Foxp3+TregsGST vaccineSchistosoma japonicum

Identifiers

PMID28825137
OpenAlexW2747256489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.