Evidence map›Paper›PMID 28825053›Full record

ArticleJournal of immunology research and therapy2017

The Basics of Artificial Antigen Presenting Cells in T Cell-Based Cancer Immunotherapies.

Lillian R Neal, Stefanie R Bailey, Megan M Wyatt, Jacob S Bowers, Kinga Majchrzak, Michelle H Nelson, Carl Haupt, Chrystal M Paulos, Juan C Varela

Abstract read
In one paragraph

Article in Journal of immunology research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lillian R NealDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Stefanie R BaileyDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Megan M WyattDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Jacob S BowersDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Kinga MajchrzakDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Michelle H NelsonDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Carl HauptDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Chrystal M PaulosDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.
Juan C VarelaDepartment of Microbiology & Immunology, Medical University of South Carolina, Charleston, SC 29425.

Funding

MUSC/HCC Paul Calabresi Clinical Oncology Training Program PlanK12CA157688 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LOCKHART, ALBERT CRAIG, WRANGLE, JOHN M. · 2013 to 2022
$4.3M
Mechanisms of durable antitumor immunity via CD26hiCD4+ T cellsR01CA208514 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2016 to 2020
$1.7M
Costimulatory mechanisms of antitumor Th17 cell immunityR01CA175061 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2013 to 2017
$1.5M
NCI NIH HHS R01 CA175061NCI NIH HHS R01 CA208514
6 · The paper itself

Abstract

Adoptive T cell transfer (ACT) can mediate objective responses in patients with advanced malignancies. There have been major advances in this field, including the optimization of the

Indexed as

Adoptive cell transferArtificial antigen presenting cells (aAPCs)Cancer immunologyImmunotherapyT cells

Identifiers

PMID28825053
PMCPMC5560309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.