ArticleSchizophrenia research. Cognition2017
Speed and capacity of working memory and executive function in schizophrenia compared to unipolar depression.
Article in Schizophrenia research. Cognition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Shared and distinct brain fMRI response during performance of working memory tasks in adult patients with schizophrenia and major depressive disorder.Human brain mapping · 2021Pooled it
- Distinct association of plasma BDNF concentration and cognitive function in depressed patients treated with vortioxetine or escitalopram.Psychopharmacology · 2021Trial
- Understanding Anticipatory Anhedonia in Schizophrenia and Depression: Linking Reward Representation Maintenance from a Transdiagnostic Perspective.Schizophrenia bulletin · 2026Article
- Differential patterns of executive dysfunction across depressive phenotype in schizophrenia and major depressive disorder.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Neuropsychological performance in women at risk of postpartum depression and postpartum psychosis.Archives of women's mental health · 2025Article
- Differential expression of diacylglycerol kinase ζ is involved in inferior parietal lobule-related dysfunction in schizophrenia with cognitive impairments.BMC psychiatry · 2023Article
- Cognitive Remediation in Psychiatric Disorders: State of the Evidence, Future Perspectives, and Some Bold Ideas.Brain sciences · 2022Review
- Sex differences in association between cognitive impairment and clinical correlates in Chinese patients with first-episode drug-naïve schizophrenia.Annals of general psychiatry · 2021Article
- Executive functions predict verbal fluency scores in healthy participants.Scientific reports · 2020Article
- Relationships between abnormal neural activities and cognitive impairments in patients with drug-naive first-episode schizophrenia.BMC psychiatry · 2020Article
- What cognitive processes are "sluggish" in sluggish cognitive tempo?Journal of consulting and clinical psychology · 2019Article
- Amplitude of low-frequency fluctuation (ALFF) may be associated with cognitive impairment in schizophrenia: a correlation study.BMC psychiatry · 2019Article
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Authors and funding
6 authors.
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Abstract
Schizophrenia is associated with deficits in working memory (WM) and executive functioning (EF) that are present from prodrome to chronic stages of the disease and are related to social and occupational functioning. Recent empirical findings suggest that schizophrenia patients might suffer from a specific speed deficit regarding WM operations that also affects EF. To test this hypothesis, executive functioning (EF) and working memory (WM) performance of 20 schizophrenia (SC) patients, 20 patients suffering from Major Depressive Disorder (MDD) and 40 healthy control (HC) subjects were compared. While schizophrenia patients performed worse in the measure of EF, no difference between the SC and the MDD patients was found regarding WM capacity. However, the SC group was shown to have an impaired speed in encoding, retrieval and manipulation of WM contents compared to the HC group whereas the MDD group showed no such deficit. Furthermore, while in the MDD group only WM capacity was linked to EF performance, in the SC group EF was determined by both WM capacity and WM speed. Hence, increasing the speed of WM operations might be a fruitful target for future therapeutic interventions, and assessing not only the capacity but also the speed of WM might be helpful in identifying candidates for endophenotypic cognitive markers of SC.
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