Evidence map›Paper›PMID 28824745›Full record

ArticleWorld journal of hepatology2017

Outcomes of pregnancy in patients with known Budd-Chiari syndrome.

Faisal Khan, Ian Rowe, Bill Martin, Ellen Knox, Tracey Johnston, Charlie Elliot, Will Lester, Frederick Chen, Simon Olliff, Homoyon Mehrzad and 2 more

Open access · diamondAbstract read
In one paragraph

Article in World journal of hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Pregnancy AfterJournal of medical cases · 2026
    Article
  3. Challenges in the management of vascular liver disorders in women in the reproductive period.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  4. Article
  5. Article
  6. Management of splanchnic vein thrombosis.JHEP reports : innovation in hepatology · 2023
    Review
  7. Pregnancy outcomes in patients with Budd-Chiari syndrome: A tertiary care experience.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  8. Article
  9. State of the Art in Hepatic Dysfunction in Pregnancy.Healthcare (Basel, Switzerland) · 2021
    Review
  10. Management of pregnancy in women with cirrhosis.United European gastroenterology journal · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Faisal KhanFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Ian RoweFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Bill MartinFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Ellen KnoxFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Tracey JohnstonFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Charlie ElliotFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Will LesterFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Frederick ChenFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Simon OlliffFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Homoyon MehrzadFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Zergham ZiaFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Dhiraj TripathiFaisal Khan, Ian Rowe, Dhiraj Tripathi, Liver Unit, Queen Elizabeth Hospital, Birmingham B15 2GW, United Kingdom.
Queen Elizabeth Hospital Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyse the risk of pregnancy (a prothrombotic state) in patients with Budd-Chiari Syndrome (BCS).

methodsRetrospective study of pregnancy in women with known BCS at single center from January 2001 to December 2015.

resultsOut of 53 females with BCS, 7 women had 16 pregnancies. Median age at diagnosis of BCS in these women was 25 years (range 21-34 years). At least one causal factor for BCS was identified in 6 women (86%). Six women had undergone radiological decompressive treatment. All patients had anticoagulation. Six fetuses were lost before 20 wk gestation in 2 women. There were 9 deliveries over 32 wk gestation and one delivery at 27 wk. All infants did well. Seven babies were born by emergency caesarean section. There were no cases of thrombosis. Two patients had notable vaginal (PV) bleeding in 3 pregnancies. None of the patients had variceal haemorrhage. Two patients were diagnosed with pulmonary hypertension, one during pregnancy and the other in the post-partum period. There was no maternal mortality.

conclusionMaternal outcomes in patients with treated BCS are favourable and fetal outcomes beyond 20 wk gestation are good. There has been increased rate of caesarean section. Pulmonary hypertension is an important finding that needs further validation. These patients should be managed in centers experienced in treating high-risk pregnancies.

Indexed as

Budd-Chiari syndromePortal hypertensionPregnancyPulmonary hypertensionThrombophilia

Identifiers

PMID28824745
PMCPMC5545139
OpenAlexW2739705320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.