Evidence map›Paper›PMID 28824737›Full record

ReviewThe EPMA journal2017

Mystery of the brain metastatic disease in breast cancer patients: improved patient stratification, disease prediction and targeted prevention on the horizon?

Jiri Polivka, Milena Kralickova, Jiri Polivka, Christina Kaiser, Walther Kuhn, Olga Golubnitschaja

Open access · hybridAbstract readReview
In one paragraph

Review in The EPMA journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

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  15. Controlling metastatic cancer: the role of phytochemicals in cell signaling.Journal of cancer research and clinical oncology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jiri PolivkaDepartment of Histology and Embryology, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.
Milena KralickovaDepartment of Histology and Embryology, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.
Jiri PolivkaDepartment of Neurology, Faculty Hospital Plzen, Plzen, Czech Republic.
Christina KaiserDepartment of Gynaecology, Medical Faculty, Friedrich-Wilhelms-University of Bonn, Bonn, Germany.
Walther KuhnDepartment of Gynaecology, Medical Faculty, Friedrich-Wilhelms-University of Bonn, Bonn, Germany.
Olga GolubnitschajaBreast Cancer Research Centre, Friedrich-Wilhelms-University of Bonn, Bonn, Germany.
Charles University · CZUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The breast cancer (BC) diagnosis currently experiences the epidemic evolution with more than half of million deaths each year. Despite screening programmes applied and treatments available, breast cancer patients frequently develop distant metastases. The brain is one of the predominant sites of the metastatic spread recorded for more than 20% of BC patients, in contrast to the general population, where brain tumours are rarely diagnosed. Although highly clinically relevant, the brain tumour mystery in the cohort of breast cancer patients has not been yet adequately explained. This review summarises currently available information on the risk factors predicting brain metastases in BC patients to motivate the relevant scientific areas to explore the data/facts available and elucidate disease-specific mechanisms that are of a great clinical utility.

Indexed as

Brain metastasisBreast cancerMultilevel diagnosticsPatient stratificationPredictive preventive and personalised medicineRisk factors

Identifiers

PMID28824737
PMCPMC5545987
OpenAlexW2594973992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.