ArticleFrontiers in genetics2017
Environment-Dependent Genotype-Phenotype Associations in Avian Breeding Time.
Article in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Genotype-Phenotype-Environment Associations and Potential Local Adaptation Signals in the Mesquite Lizard Along the Eastern Trans-Mexican Volcanic Belt.Molecular ecology · 2026Article
- The Genetic and Morphological Basis of Local Adaptation to Elevational Extremes in an Alpine Finch.Ecology and evolution · 2026Article
- Mapping multitissue regulatory variants reveals a liver-centric coexpression network associated with duck egg-laying performance.Genome research · 2025Article
- Genetic and epigenetic differentiation in response to genomic selection for avian lay date.Evolutionary applications · 2024Article
- Genotypes selected for early and late avian lay date differ in their phenotype, but not fitness, in the wild.Science advances · 2023Article
- Metabolic Variations among Three New Tea Varieties Cultivated in Shandong, China.Foods (Basel, Switzerland) · 2023Article
- A Metabolomics Approach and Chemometric Tools for Differentiation of Barley Cultivars and Biomarker Discovery.Metabolites · 2021Article
- Rapid changes in DNA methylation associated with the initiation of reproduction in a small songbird.Molecular ecology · 2021Article
- The genetic regulation of avian migration timing: combining candidate genes and quantitative genetic approaches in a long-distance migrant.Oecologia · 2021Article
- Continent-wide genomic signatures of adaptation to urbanisation in a songbird across Europe.Nature communications · 2021Article
- Metabolomics for Biomarker Discovery: Key Signatory Metabolic Profiles for the Identification and Discrimination of Oat Cultivars.Metabolites · 2021Article
- Polygenic basis for adaptive morphological variation in a threatened Aotearoa | New Zealand bird, the hihi (Proceedings. Biological sciences · 2020Article
- Exploration of tissue-specific gene expression patterns underlying timing of breeding in contrasting temperature environments in a song bird.BMC genomics · 2019Article
- Temporally replicated DNA methylation patterns in great tit using reduced representation bisulfite sequencing.Scientific data · 2019Article
- On the importance of time scales when studying adaptive evolution.Evolution letters · 2019Article
- Genomic selection on breeding time in a wild bird population.Evolution letters · 2019Article
- Great tits and the city: Distribution of genomic diversity and gene-environment associations along an urbanization gradient.Evolutionary applications · 2018Article
- Understanding Evolutionary Impacts of Seasonality: An Introduction to the Symposium.Integrative and comparative biology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding how genes shape phenotypes is essential to assess the evolutionary potential of a trait. Identifying the genes underlying quantitative behavioral or life-history traits has, however, proven to be a major challenge. The majority of these traits are phenotypically plastic and different parts of the genome can be involved in shaping the trait under different environmental conditions. These variable genotype-phenotype associations could be one explanation for the limited success of genome-wide association studies in such traits. We here use avian seasonal timing of breeding, a trait that is highly plastic in response to spring temperature, to explore effects of such genotype-by-environment interactions in genome-wide association studies. We genotyped 2045 great tit females for 384081 single nucleotide polymorphisms (SNPs) and recorded their egg-laying dates in the wild. When testing for associations between SNPs and egg-laying dates, no SNP reached genome-wide significance. We then explored whether SNP effects were modified by annual spring temperature by formally testing for an interaction between SNP effect and temperature. The models including the SNP
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.