Evidence map›Paper›PMID 28824693›Full record

ReviewFrontiers in plant science2017

Mechanisms of Selenium Enrichment and Measurement in Brassicaceous Vegetables, and Their Application to Human Health.

Melanie Wiesner-Reinhold, Monika Schreiner, Susanne Baldermann, Dietmar Schwarz, Franziska S Hanschen, Anna P Kipp, Daryl D Rowan, Kerry L Bentley-Hewitt, Marian J McKenzie

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Joint Cultivation ofPlants (Basel, Switzerland) · 2022
    Article
  13. Review
  14. Review
  15. Article
  16. Antitumor Effects of Selenium.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Melanie Wiesner-ReinholdPlant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental CropsGrossbeeren, Germany.
Monika SchreinerPlant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental CropsGrossbeeren, Germany.
Susanne BaldermannPlant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental CropsGrossbeeren, Germany.
Dietmar SchwarzFunctional Plant Biology, Leibniz Institute of Vegetable and Ornamental CropGrossbeeren, Germany.
Franziska S HanschenPlant Quality and Food Security, Leibniz Institute of Vegetable and Ornamental CropsGrossbeeren, Germany.
Anna P KippDepartment of Molecular Nutritional Physiology, Institute of Nutrition, Friedrich Schiller University JenaJena, Germany.
Daryl D RowanFood Innovation, The New Zealand Institute for Plant & Food Research LimitedPalmerston North, New Zealand.
Kerry L Bentley-HewittFood Innovation, The New Zealand Institute for Plant & Food Research LimitedPalmerston North, New Zealand.
Marian J McKenzieFood Innovation, The New Zealand Institute for Plant & Food Research LimitedPalmerston North, New Zealand.
Leibniz Institute of Vegetable and Ornamental Crops · DEPlant & Food Research · NZFriedrich Schiller University Jena · DEUniversity of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium (Se) is an essential micronutrient for human health. Se deficiency affects hundreds of millions of people worldwide, particularly in developing countries, and there is increasing awareness that suboptimal supply of Se can also negatively affect human health. Selenium enters the diet primarily through the ingestion of plant and animal products. Although, plants are not dependent on Se they take it up from the soil through the sulphur (S) uptake and assimilation pathways. Therefore, geographic differences in the availability of soil Se and agricultural practices have a profound influence on the Se content of many foods, and there are increasing efforts to biofortify crop plants with Se. Plants from the Brassicales are of particular interest as they accumulate and synthesize Se into forms with additional health benefits, such as methylselenocysteine (MeSeCys). The Brassicaceae are also well-known to produce the glucosinolates; S-containing compounds with demonstrated human health value. Furthermore, the recent discovery of the selenoglucosinolates in the Brassicaceae raises questions regarding their potential bioefficacy. In this review we focus on Se uptake and metabolism in the Brassicaceae in the context of human health, particularly cancer prevention and immunity. We investigate the close relationship between Se and S metabolism in this plant family, with particular emphasis on the selenoglucosinolates, and consider the methodologies available for identifying and quantifying further novel Se-containing compounds in plants. Finally, we summarize the research of multiple groups investigating biofortification of the Brassicaceae and discuss which approaches might be most successful for supplying Se deficient populations in the future.

Indexed as

analytical methodsbiofortificationBrassica vegetablescancerglucosinolateshuman healthimmune systemselenium

Identifiers

PMID28824693
PMCPMC5540907
OpenAlexW2742123723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.