Evidence map›Paper›PMID 28824692›Full record

ArticleFrontiers in plant science2017

Genome Editing in Cotton with the CRISPR/Cas9 System.

Wei Gao, Lu Long, Xinquan Tian, Fuchun Xu, Ji Liu, Prashant K Singh, Jose R Botella, Chunpeng Song

Abstract read
In one paragraph

Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Genetic basis and role of exotic accessions in cultivated cotton fiber quality improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
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  14. Positive roles of the CaMolecular plant pathology · 2024
    Article
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  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei GaoState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.
Lu LongState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.
Xinquan TianState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.
Fuchun XuState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.
Ji LiuState Key Laboratory of Cotton Biology, Institute of Cotton Research of Chinese Academy of Agricultural SciencesAnyang, China.
Prashant K SinghState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.
Jose R BotellaSchool of Agriculture and Food Sciences, University of Queensland, BrisbaneQLD, Australia.
Chunpeng SongState Key Laboratory of Cotton Biology, Henan Key Laboratory of Plant Stress Biology, School of Life Sciences, Henan UniversityKaifeng, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome editing is an important tool for gene functional studies as well as crop improvement. The recent development of the CRISPR/Cas9 system using single guide RNA molecules (sgRNAs) to direct precise double strand breaks in the genome has the potential to revolutionize agriculture. Unfortunately, not all sgRNAs are equally efficient and it is difficult to predict their efficiency by bioinformatics. In crops such as cotton (

Indexed as

cottonCRISPR/Cas9deletiongenome editinginsertionmutagenesistransient transform

Identifiers

PMID28824692
PMCPMC5541054

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.