ArticleFrontiers in immunology2017
Dynamics of Recent Thymic Emigrants in Young Adult Mice.
Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Multiscale physiologically-based model of age-dependent CD4+ T-lymphocyte homeostasis.Frontiers in immunology · 2026Article
- Comprehensive Flow Cytometric, Immunohistologic, and Molecular Assessment of Thymus Function in Rhesus Macaques.ImmunoHorizons · 2024Article
- Modeling T Cell Fate.Annual review of immunology · 2023Review
- Standing on the shoulders of mice.Immunity · 2022Review
- Article
- Early age-related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Are homeostatic mechanisms aiding the reconstitution of the T-cell pool during lymphopenia in humans?Frontiers in immunology · 2022Review
- Building a T cell compartment: how immune cell development shapes function.Nature reviews. Immunology · 2020Review
- When few survive to tell the tale: thymus and gonad as auditioning organs: historical overview.Theory in biosciences = Theorie in den Biowissenschaften · 2020Review
- The full spectrum of human naive T cells.Nature reviews. Immunology · 2018Review
- Age is not just a number: Naive T cells increase their ability to persist in the circulation over time.PLoS biology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The peripheral naive T-cell pool is generally thought to consist of a subpopulation of recent thymic emigrants (RTEs) and a subpopulation of mature naive (MN) T cells with different dynamics. Thymus transplantation and adoptive transfer studies in mice have provided contradicting results, with some studies suggesting that RTEs are relatively short-lived cells, while another study suggested that RTEs have a survival advantage. We here estimate the death rates of RTE and MN T cells by performing both thymus transplantations and deuterium labeling experiments in mice of at least 12 weeks old, an age at which the size of the T-cell pool has stabilized. For CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.