Evidence map›Paper›PMID 28824534›Full record

ArticleFrontiers in neurology2017

Eyetracking Metrics in Young Onset Alzheimer's Disease: A Window into Cognitive Visual Functions.

Ivanna M Pavisic, Nicholas C Firth, Samuel Parsons, David Martinez Rego, Timothy J Shakespeare, Keir X X Yong, Catherine F Slattery, Ross W Paterson, Alexander J M Foulkes, Kirsty Macpherson and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A novel eye-tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  10. Review
  11. Article
  12. Ocular changes as potential biomarkers for early diagnosis of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  13. Article
  14. Eye Tracking as a Tool for Detecting Alzheimer's Disease in People With Down Syndrome.Journal of intellectual disability research : JIDR · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Ivanna M PavisicDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Nicholas C FirthCentre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom.
Samuel ParsonsCentre for Computational Statistics and Machine Learning, Faculty of Engineering Science, Department of Computer Science, University College London, London, United Kingdom.
David Martinez RegoCentre for Computational Statistics and Machine Learning, Faculty of Engineering Science, Department of Computer Science, University College London, London, United Kingdom.
Timothy J ShakespeareDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Keir X X YongDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Catherine F SlatteryDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Ross W PatersonDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Alexander J M FoulkesDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Kirsty MacphersonDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Amelia M CartonDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Daniel C AlexanderCentre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom.
John Shawe-TaylorCentre for Computational Statistics and Machine Learning, Faculty of Engineering Science, Department of Computer Science, University College London, London, United Kingdom.
Nick C FoxDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Jonathan M SchottDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Sebastian J CrutchDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
Silvia PrimativoDementia Research Centre, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, London, United Kingdom.
University College London · GBUK Dementia Research Institute · GB

Funding

Medical Research Council MR/L023784/2
6 · The paper itself

Abstract

Young onset Alzheimer's disease (YOAD) is defined as symptom onset before the age of 65 years and is particularly associated with phenotypic heterogeneity. Atypical presentations, such as the clinic-radiological visual syndrome posterior cortical atrophy (PCA), often lead to delays in accurate diagnosis. Eyetracking has been used to demonstrate basic oculomotor impairments in individuals with dementia. In the present study, we aim to explore the relationship between eyetracking metrics and standard tests of visual cognition in individuals with YOAD. Fifty-seven participants were included: 36 individuals with YOAD (

Indexed as

classification modelcognitive visual functionseye movementseyetracking metricsmachine learningyoung onset Alzheimer’s disease

Identifiers

PMID28824534
PMCPMC5545969
OpenAlexW2743629169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.