ArticleFrontiers in psychiatry2017
Altered Gray-Matter Volumes Associated With Betel Quid Dependence.
Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Altered Functional Connectivity in the Reward Circuit in Betel Quid-Dependent Chewers.Addiction biology · 2026Article
- Understanding betel nut addiction: a review of harmful consequences, underlying neurobiology, and emerging intervention strategies.Translational psychiatry · 2026Review
- Altered orbitofrontal and pars opercularis cortical thickness in betel quid dependence chewers.Therapeutic advances in psychopharmacology · 2024Article
- Mapping white matter structural and network alterations in betel quid-dependent chewers using high angular resolution diffusion imaging.Frontiers in psychiatry · 2022Article
- A multivariate pattern analysis of resting-state functional MRI data in Naïve and chronic betel quid chewers.Brain imaging and behavior · 2021Article
- Betel Quid Health Risks of Insulin Resistance Diseases in Poor Young South Asian Native and Immigrant Populations.International journal of environmental research and public health · 2020Review
- Reduced Cortical Thickness in the Right Caudal Middle Frontal Is Associated With Symptom Severity in Betel Quid-Dependent Chewers.Frontiers in psychiatry · 2020Article
- Higher Trait Impulsivity and Altered Frontostriatal Connectivity in Betel-Quid Dependent Individuals.Frontiers in human neuroscience · 2020Article
- Dysfunction of the Prefrontal Cortex in Betel-Quid-Dependent Chewers.Frontiers in psychiatry · 2020Article
- Brain Function Network and Young Adult Smokers: A Graph Theory Analysis Study.Frontiers in psychiatry · 2019Article
- Structural and Functional Connectivity Between the Amygdala and Orbital Frontal Cortex in Burning Mouth Syndrome: An fMRI Study.Frontiers in psychology · 2019Article
- Structural and Functional Alterations in Betel-Quid Chewers: A Systematic Review of Neuroimaging Findings.Frontiers in psychiatry · 2019Article
- White Matter Integrity Deficit Associated with Betel Quid Dependence.Frontiers in psychiatry · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Betel quid (BQ) is one of the most commonly consumed psychoactive substances. It has been suggested to be associated with various health issues, especially oral cancer. Evidence also points to possible decreased cognitive functions after long-term BQ chewing, such as attention and inhibition control. The present study aims to investigate the brain structure basis of BQ chewing in Hunan province of China. Twenty-five BQ chewers and 25 controls were recruited to participate in this study. Voxel-based morphormetry analysis revealed that there were three key regions showing structural differences between BQ chewers and controls, including bilateral dorsolateral prefrontal cortex (DLPFC)/insula, ventral medial prefrontal cortex, and left orbitofrontal cortex. Moreover, the GMV in the DLPFC could potentially predict BQ dependence scores, level of daily BQ chewing, and history of BQ chewing. These results suggested that participants who showed BQ chewing dependence may have deficit in inhibition control and affective decision-making, and the level of deficit was dependent on the level of daily BQ chewing, and history of BQ chewing. Understanding the neurobiology features of BQ chewing would help us develop novel ways to diagnose and prevent BQ dependence.
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