ReviewFrontiers in physiology2017
Reviewing the Role of the Efferent Vestibular System in Motor and Vestibular Circuits.
Review in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 48 citations in OpenAlex.
- Auditory contributions to postural and locomotor control: from basic research to clinical applications.Experimental brain research · 2026Review
- Selective genetic targeting of the mouse efferent vestibular nucleus identifies monosynaptic inputs and indicates function as multimodal integrator.Journal of neurophysiology · 2026Article
- Electrophysiological Characterization of Murine Vestibular Efferent Neurons and Modulation by Acute Peripheral Vestibular Deprivation.Neuroscience bulletin · 2026Article
- Neurotransmitter regulatory networks in persistent postural-perceptual dizziness: potential mechanisms and therapeutic implications.Frontiers in neurology · 2026Review
- Perspective: Hippocampal theta rhythm as a potential vestibuloacoustic biomarker of anxiety.The European journal of neuroscience · 2025Review
- Pharmacological regeneration of sensory hair cells restores afferent innervation and vestibular function.The Journal of clinical investigation · 2024Article
- A New Perspective to Interpret How the Vestibular Efferent System Correlates the Complexity of Routine Balance Maintenance with Management of Emergency Fall Prevention Strategies.Audiology research · 2024Article
- Aged mice are less susceptible to motion sickness and show decreased efferent vestibular activity compared to young adults.Brain and behavior · 2023Article
- Molecular and Functional Changes to Postsynaptic Cholinergic Signaling in the Vestibular Sensory Organs of Aging C57BL/6 Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system.eLife · 2023Article
- Subtle alterations of vestibulomotor functioning in conductive hearing loss.Frontiers in neuroscience · 2023Article
- Context-independent encoding of passive and active self-motion in vestibular afferent fibers during locomotion in primates.Nature communications · 2022Article
- The Larval Zebrafish Vestibular System Is a Promising Model to Understand the Role of Myelin in Neural Circuits.Frontiers in neuroscience · 2022Article
- Differences in the Structure and Function of the Vestibular Efferent System Among Vertebrates.Frontiers in neuroscience · 2021Review
- The Long and Winding Road-Vestibular Efferent Anatomy in Mice.Frontiers in neural circuits · 2021Article
- Efferent synaptic transmission at the vestibular type II hair cell synapse.Journal of neurophysiology · 2020Article
- A review of efferent cholinergic synaptic transmission in the vestibular periphery and its functional implications.Journal of neurophysiology · 2020Review
- Identification of New Biomarkers of Posturo-Locomotor Instability in a Rodent Model of Vestibular Pathology.Frontiers in neurology · 2020Article
- Efferent Inputs Are Required for Normal Function of Vestibular Nerve Afferents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Sensorimotor anatomy of gait, balance, and falls.Handbook of clinical neurology · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Efferent circuits within the nervous system carry nerve impulses from the central nervous system to sensory end organs. Vestibular efferents originate in the brainstem and terminate on hair cells and primary afferent fibers in the semicircular canals and otolith organs within the inner ear. The function of this efferent vestibular system (EVS) in vestibular and motor coordination though, has proven difficult to determine, and remains under debate. We consider current literature that implicate corollary discharge from the spinal cord through the efferent vestibular nucleus (EVN), and hint at a potential role in overall vestibular plasticity and compensation. Hypotheses range from differentiating between passive and active movements at the level of vestibular afferents, to EVS activation under specific behavioral and environmental contexts such as arousal, predation, and locomotion. In this review, we summarize current knowledge of EVS circuitry, its effects on vestibular hair cell and primary afferent activity, and discuss its potential functional roles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.