ArticleFrontiers in aging neuroscience2017
ApoE rs429358 and rs7412 Polymorphism and Gender Differences of Serum Lipid Profile and Cognition in Aging Chinese Population.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 50 citations in OpenAlex.
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- Unraveling the genetic interplay and therapeutic potentials between major depressive disorder and metabolic syndrome: multi-ancestry and multi-trait genome-wide association analyses.BMC psychiatry · 2026Article
- Proteome-wide association studies for blood lipids and comparison with transcriptome-wide association studies.HGG advances · 2025Article
- Genetic variations of low-density lipoprotein cholesterol on metabolic disorders in obstructive sleep apnea.Nutrition & metabolism · 2024Article
- Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.Frontiers in nutrition · 2023Article
- Suicide-Related Single Nucleotide Polymorphisms,Genes · 2022Article
- Association betweenInternational journal of molecular sciences · 2022Article
- Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults.BMC psychiatry · 2022Article
- Long-covid cognitive impairment: Cognitive assessment and apolipoprotein E (APOE) genotyping correlation in a Brazilian cohort.Frontiers in psychiatry · 2022Article
- Association between risk polymorphisms for neurodegenerative diseases and cognition in colombian patients with frontotemporal dementia.Frontiers in neurology · 2022Article
- Associations of circadian rest/activity rhythms with cognition in middle-aged and older adults: Demographic and genetic interactions.Frontiers in neuroscience · 2022Article
- The effects of genetic polymorphisms of APOE on circulating lipid levels in middle-aged and elderly chinese Fujian Han population: toward age- and sex-personalized management.Lipids in health and disease · 2021Article
- Association of APOE genotype with lipid profiles and type 2 diabetes mellitus in a Korean population.Genes & genomics · 2021Article
- Article
- Interaction between APOE ε4 and dietary protein intake on cognitive decline: A longitudinal cohort study.Clinical nutrition (Edinburgh, Scotland) · 2021Article
- Impact ofViruses · 2021Article
- The relationship between ApoE gene polymorphism and the efficacy of statins controlling hyperlipidemia.American journal of translational research · 2021Article
- Apolipoprotein E Genotype, Meat, Fish, and Egg Intake in Relation to Mortality Among Older Adults: A Longitudinal Analysis in China.Frontiers in medicine · 2021Article
- Identifying Imaging Genetics Biomarkers of Alzheimer's Disease by Multi-Task Sparse Canonical Correlation Analysis and Regression.Frontiers in genetics · 2021Article
- Childhood trauma interacts with ApoE to influence neurocognitive function in women living with HIV.Journal of neurovirology · 2019Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ApoE gene polymorphism has been reportedly associated with serum lipids and cognition. However, very few studies have explored the combined effects of ApoE gene polymorphism and gender on serum lipid profile with subsequent impacts on cognition in Chinese population. A total of 1,000 Chinese community dwellers aged 55 years and above were recruited in this cross-sectional study. Demographic information of the participants was collected using well designed self-administered questionnaires. The Montreal Cognitive Assessment (MoCA) test was employed to evaluate the cognitive status of the participants. Semi-quantitative food frequency questionnaire (FFQ) was used to obtain the dietary intake information. Fasting venous blood samples were taken for ApoE genotyping and serum lipid measurements. Significant gender differences in cognition, serum lipid profile and dietary fat-rich foods consumption were observed (
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