ReviewFrontiers in human neuroscience2017
When Null Hypothesis Significance Testing Is Unsuitable for Research: A Reassessment.
Review in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
82 citing papers in PubMed.
- Bone and non-contractile soft tissue changes following open kinetic chain resistance training and testosterone treatment in spinal cord injury: an exploratory study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Trial
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- Feasibility and acceptability of a rural palliative care intervention for patients with heart failure (RuPAL-HF).BMC palliative care · 2026Article
- The Latina physician wage chasm: a secondary analysis of the American Community Survey.Academic medicine : journal of the Association of American Medical Colleges · 2026Article
- Neurobiology of co-morbid stress and a western diet in mice: mitochondrial, proteomic and behavioral outcomes.Metabolic brain disease · 2026Article
- The Contribution of Bayesian Methods in Solving the Paradoxes of Classical Statistical Tests in Biomedical Research.Journal of clinical medicine · 2026Article
- Impact of self-reported cannabis use on veterans' intensive PTSD treatment outcomes.Psychological trauma : theory, research, practice and policy · 2026Article
- Article
- Untested Assumptions and Tenuous Evidence: A Critique of the Dual-Process Account of Moral Judgment.Behavioral sciences (Basel, Switzerland) · 2025Review
- Disparity between statistical significance and clinical importance in published randomised controlled trials: a methodological study.BMJ open · 2025Article
- Alternative to the statistical mass confusion of testing for "no effect".The Journal of cell biology · 2025Article
- A phylogenetic approach to comparative genomics.Nature reviews. Genetics · 2025Review
- The null hypothesis significance test and the dichotomization of the p-value: Errare Humanum Est.Revista peruana de medicina experimental y salud publica · 2025Review
- Improving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle.International journal of molecular sciences · 2025Review
- Modeling frameworks in nutritional epidemiology matter: comparing isotemporal and time-lagged Bayesian and frequentist approaches of carbohydrate intake and adiposity.Frontiers in nutrition · 2025Article
- Article
- Sociodemographic Variables in Offender and Non-Offender Patients Diagnosed with Schizophrenia Spectrum Disorders-An Explorative Analysis Using Machine Learning.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Beyond regression: Unpacking research of human complex systems with qualitative comparative analysis.Heliyon · 2024Article
- Methylphenidate and Short-Term Cardiovascular Risk.JAMA network open · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Null hypothesis significance testing (NHST) has several shortcomings that are likely contributing factors behind the widely debated replication crisis of (cognitive) neuroscience, psychology, and biomedical science in general. We review these shortcomings and suggest that, after sustained negative experience, NHST should no longer be the default, dominant statistical practice of all biomedical and psychological research. If theoretical predictions are weak we should not rely on all or nothing hypothesis tests. Different inferential methods may be most suitable for different types of research questions. Whenever researchers use NHST they should justify its use, and publish pre-study power calculations and effect sizes, including negative findings. Hypothesis-testing studies should be pre-registered and optimally raw data published. The current statistics lite educational approach for students that has sustained the widespread, spurious use of NHST should be phased out.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.