Evidence map›Paper›PMID 28824387›Full record

ArticleFrontiers in systems neuroscience2017

Behavioral Sensitization to the Disinhibition Effect of Ethanol Requires the Dopamine/Ecdysone Receptor in

Gissel P Aranda, Samantha J Hinojos, Paul R Sabandal, Peter D Evans, Kyung-An Han

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Ethanol Behavioral Responses inCold Spring Harbor protocols · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Flying Together:International journal of molecular sciences · 2020
    Review
  9. Review
  10. The Neurotransmitters Involved inFrontiers in behavioral neuroscience · 2020
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gissel P ArandaNeuromodulation Disorders Cluster at Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El PasoEl Paso, TX, United States.
Samantha J HinojosNeuromodulation Disorders Cluster at Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El PasoEl Paso, TX, United States.
Paul R SabandalNeuromodulation Disorders Cluster at Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El PasoEl Paso, TX, United States.
Peter D EvansThe Inositide Laboratory, The Babraham InstituteCambridge, United Kingdom.
Kyung-An HanNeuromodulation Disorders Cluster at Border Biomedical Research Center, Department of Biological Sciences, University of Texas at El PasoEl Paso, TX, United States.
The University of Texas at El Paso · USBabraham Institute · GB

Funding

TOXICOLOGY PROJECTG12RR008124 · NCRR · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 1992 to 2011
$20.8M
TCCG12MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI KIRKEN, ROBERT A. · 2012 to 2018
$19.4M
RISE Scholars Program at UTEPR25GM069621 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 2004 to 2021
$11.2M
Research Supplement to Promote Diversity in Health-Related ResearchR15AA020996 · NIAAA · UNIVERSITY OF TEXAS EL PASO · PI HAN, KYUNG-AN · 2012 to 2014
$499k
NCRR NIH HHS G12 RR008124NIAAA NIH HHS R15 AA020996NIGMS NIH HHS R25 GM069621NIMHD NIH HHS G12 MD007592
6 · The paper itself

Abstract

Male flies under the influence of ethanol display disinhibited courtship, which is augmented with repeated ethanol exposures. We have previously shown that dopamine is important for this type of ethanol-induced behavioral sensitization but the underlying mechanism is unknown. Here we report that DopEcR, an insect G-protein coupled receptor that binds to dopamine and steroid hormone ecdysone, is a major receptor mediating courtship sensitization. Upon daily ethanol administration,

Indexed as

behavioral sensitizationcourtship disinhibitionD1 receptorsdopamineDopEcRethanolmushroom bodytolerance

Identifiers

PMID28824387
PMCPMC5539124
OpenAlexW2741360897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.