Evidence map›Paper›PMID 28824290›Full record

ArticleEuropean journal of organic chemistry2016

A General Chemoenzymatic Strategy for the Synthesis of Glycosphingolipids.

Yunpeng Liu, Liuqing Wen, Lei Li, Madhusudhan Reddy Gadi, Wanyi Guan, Kenneth Huang, Zhongying Xiao, Mohui Wei, Cheng Ma, Qing Zhang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Defining substrate specificities ofOrganic chemistry frontiers : an international journal of organic chemistry · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Potassium carbonate-mediatedTetrahedron letters · 2023
    Article
  6. Article
  7. Article
  8. Oligosaccharide Synthesis and Translational Innovation.Journal of the American Chemical Society · 2019
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yunpeng LiuNational Glycoengineering Research Center, Shandong Provincial Key Lab of Carbohydrate Chemistry, and State Key Lab of Microbial Technology, Shandong University, Jinan, Shandong 250100, People's Republic of China.
Liuqing WenDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Lei LiDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Madhusudhan Reddy GadiDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Wanyi GuanDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Kenneth HuangDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Zhongying XiaoDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Mohui WeiDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Cheng MaDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Qing ZhangDepartment of Chemistry, Georgia State University, Atlanta, Georgia 30303, USA, http://lithium.gsu.edu/faculty/PWang/.
Hai YuDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA 95616, https://chenglycogroup.wordpress.com/.
Xi ChenDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA 95616, https://chenglycogroup.wordpress.com/.
Peng George WangNational Glycoengineering Research Center, Shandong Provincial Key Lab of Carbohydrate Chemistry, and State Key Lab of Microbial Technology, Shandong University, Jinan, Shandong 250100, People's Republic of China.
Junqiang FangNational Glycoengineering Research Center, Shandong Provincial Key Lab of Carbohydrate Chemistry, and State Key Lab of Microbial Technology, Shandong University, Jinan, Shandong 250100, People's Republic of China.

Funding

Biosynthesis of PolysaccharidesR01GM085267 · NIGMS · OHIO STATE UNIVERSITY · PI WANG, PENG GEORGE · 2009 to 2017
$2.4M
Oligosaccharides as antimicrobials and prebioticsR01HD065122 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2010 to 2013
$1.8M
NICHD NIH HHS R01 HD065122NIGMS NIH HHS R01 GM085267
6 · The paper itself

Abstract

A concise, prototypical, and stereoselective strategy for the synthesis of therapeutically and immunologically significant glycosphingolipids has been developed. This strategy provides a universal platform for glycosphingolipid synthesis by block coupling of enzymatically prepared free oligosaccharideglycans to lipids using glycosyl

Indexed as

chemoenzymaticenzymatic synthesisglycosphingolipidsglycosylationN-phenyltrifluoroacetimidate

Identifiers

PMID28824290
PMCPMC5560440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.