Evidence map›Paper›PMID 28824194›Full record

ArticleAdvances in physics2016

Optical methods for quantitative and label-free sensing in living human tissues: principles, techniques, and applications.

Robert H Wilson, Karthik Vishwanath, Mary-Ann Mycek

Open access · goldAbstract read
In one paragraph

Article in Advances in physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

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  11. Proceedings of SPIE--the International Society for Optical Engineering
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  12. Novel diffuse optics system for continuous tissue viability monitoring - extended recoveryProceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Robert H WilsonBeckman Laser Institute, University of California, Irvine, Irvine, CA, USA.
Karthik VishwanathDepartment of Physics, Miami University, Oxford, OH, USA.
Mary-Ann MycekDepartment of Biomedical Engineering, Applied Physics Program, University of Michigan, Ann Arbor, MI, USA.
Miami University · USUniversity of California, Irvine · USUniversity of Michigan · US

Funding

NRSA Training CoreTL1TR001415 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, HEAD, ELIZABETH · 2015 to 2023
$4.2M
Optical Surgical Probe for Assessing Human Oral Mucosa Graft VascularizationR44DE021935 · NIDCR · RADIATION MONITORING DEVICES, INC. · PI CHRISTIAN, JAMES F · 2014 to 2015
$1.3M
NCATS NIH HHS TL1 TR001415NIDCR NIH HHS R44 DE021935
6 · The paper itself

Abstract

We present an overview of quantitative and label-free optical methods used to characterize living biological tissues, with an emphasis on emerging applications in clinical tissue diagnostics. Specifically, this review focuses on diffuse optical spectroscopy, imaging, and tomography, optical coherence-based techniques, and non-linear optical methods for molecular imaging. The potential for non- or minimally-invasive assessment, quantitative diagnostics, and continuous monitoring enabled by these tissue-optics technologies provides significant promise for continued clinical translation.

Indexed as

coherent anti-stokes Ramandiffuse correlation spectroscopydiffuse optical spectroscopylaser speckle imagingmulti-photon microscopysecond harmonic generationtissue optics

Identifiers

PMID28824194
PMCPMC5560608
OpenAlexW2507854479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.