Evidence map›Paper›PMID 28824078›Full record

ArticleInternal medicine (Tokyo, Japan)2017

The Complete Remission of Acquired Immunodeficiency Syndrome-associated Isolated Central Nervous System Lymphomatoid Granulomatosis: A Case Report and Review of the Literature.

Yasuhiro Kano, Minori Kodaira, Atsuhito Ushiki, Makoto Kosaka, Mitsunori Yamada, Kunihiko Shingu, Hiroshi Nishihara, Masayuki Hanaoka, Yoshiki Sekijima

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Primary central nervous system lymphomatoid granulomatosis: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yasuhiro KanoDepartment of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan.
Minori KodairaDepartment of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan.
Atsuhito UshikiFirst Department of Internal Medicine, Shinshu University School of Medicine, Japan.
Makoto KosakaFirst Department of Internal Medicine, Shinshu University School of Medicine, Japan.
Mitsunori YamadaDepartment of Brain Disease Research, Shinshu University School of Medicine, Japan.
Kunihiko ShinguDepartment of Clinical Pathology, Shinshu University School of Medicine, Japan.
Hiroshi NishiharaDepartment of Translational Pathology, Hokkaido University Graduate School of Medicine, Japan.
Masayuki HanaokaFirst Department of Internal Medicine, Shinshu University School of Medicine, Japan.
Yoshiki SekijimaDepartment of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old man presented with gradually progressive aphasia one month after being diagnosed with acquired immunodeficiency syndrome (AIDS). Brain magnetic resonance imaging showed multiple brain lesions with punctate and linear enhancement. A polymerase chain reaction detected Epstein-Barr virus (EBV) in the patient's cerebrospinal fluid. A diagnosis of isolated central nervous system lymphomatoid granulomatosis (CNS-LYG) was made based on the brain biopsy findings. The complete remission of CNS-LYG was achieved by anti-retroviral therapy (ART) alone. In the present case, the development of AIDS-associated CNS-LYG was considered to have been initiated by the reactivation of EBV in the CNS under immunosuppressive conditions. The patient's condition improved with the reconstitution of the patient's immune system.

Indexed as

Acquired Immunodeficiency SyndromeBrainHerpesvirus 4, HumanHumansLymphomatoid GranulomatosisMagnetic Resonance ImagingMaleMiddle AgedRemission Inductionacquired immunodeficiency syndromeanti-retroviral therapycentral nervous systemEpstein-Barr viruslymphomatoid granulomatosis

Identifiers

PMID28824078
PMCPMC5643181

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.