Evidence map›Paper›PMID 28824071›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Persistent Gastrointestinal Angiodysplasia in Heyde's Syndrome after Aortic Valve Replacement.

Takashi Akutagawa, Takero Shindo, Kohei Yamanouchi, Masaki Hayakawa, Hiroshi Ureshino, Nanae Tsuruoka, Yasuhisa Sakata, Ryo Shimoda, Ryo Noguchi, Kojiro Furukawa and 5 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Takashi AkutagawaDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Takero ShindoDepartment of Hematology, Respiratory Medicine and Oncology, Saga University School of Medicine, Japan.
Kohei YamanouchiDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Masaki HayakawaDepartment of Transfusion Medicine, Nara Prefectural Medical College, Japan.
Hiroshi UreshinoDepartment of Hematology, Respiratory Medicine and Oncology, Saga University School of Medicine, Japan.
Nanae TsuruokaDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Yasuhisa SakataDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Ryo ShimodaDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Ryo NoguchiDepartment of Thoracic and Cardiovascular Surgery, Saga University School of Medicine, Japan.
Kojiro FurukawaDepartment of Thoracic and Cardiovascular Surgery, Saga University School of Medicine, Japan.
Shigeki MoritaDepartment of Thoracic and Cardiovascular Surgery, Saga University School of Medicine, Japan.
Ryuichi IwakiriDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Shinya KimuraDepartment of Hematology, Respiratory Medicine and Oncology, Saga University School of Medicine, Japan.
Masanori MatsumotoDepartment of Transfusion Medicine, Nara Prefectural Medical College, Japan.
Kazuma FujimotoDepartment of Internal Medicine and Gastrointestinal Endoscopy, Saga University School of Medicine, Japan.
Saga University · JPNara Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 67-year-old woman with recurrent gastrointestinal bleeding and aortic valve stenosis presented with spurting bleeding from angiodysplasia of the upper jejunum. As electrophoresis revealed decreased levels of high-molecular-weight (HMW) von Willebrand factor (VWF) multimers, she was diagnosed with Heyde's syndrome. After aortic valve replacement, her HMW VWF levels quickly recovered to normal, and the gastrointestinal bleeding ceased. However, capsule endoscopy still revealed gastrointestinal angiodysplasia six months later. This case shows that minute analyses of VWF multimers enable the diagnosis and confirmation of the resolution of Heyde's syndrome, and implies that gastrointestinal angiodysplasia can be attributed to unknown factors other than decreased VWF multimers.

Indexed as

AgedAngiodysplasiaAortic Valve StenosisCapsule EndoscopyFemaleGastrointestinal HemorrhageHeart Valve ProsthesisHumansSyndromevon Willebrand Factorvon Willebrand Factorgastrointestinal angiodysplasiaHeyde's syndromevon Willebrand factor

Identifiers

PMID28824071
PMCPMC5643169
OpenAlexW2750136471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.