Evidence map›Paper›PMID 28823902›Full record

ArticleJournal of the mechanical behavior of biomedical materials2017

A mixed-effects model approach for the statistical analysis of vocal fold viscoelastic shear properties.

Chet C Xu, Roger W Chan, Han Sun, Xiaowei Zhan

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Chet C XuDepartment of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA; Graduate Program in Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Electronic address: che.xu@utsouthwestern.edu.
Roger W ChanDepartment of Speech Language Pathology, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Han SunDepartment of Quantitative Health Sciences, the Cleveland Clinic Foundation, Cleveland, OH, 44195, USA; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
Xiaowei ZhanDepartment of Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

Funding

Hybrid scaffold gel for the treatment of vocal fold lamina propria injuryR21DC013363 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI XU, CHET CHE · 2014 to 2015
$505k
Xenogeneic scaffolds for the repair of acute vocal fold lamina propria injuryR03DC011145 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI XU, CHET CHE · 2010 to 2012
$466k
NIDCD NIH HHS R03 DC011145NIDCD NIH HHS R21 DC013363
6 · The paper itself

Abstract

A mixed-effects model approach was introduced in this study for the statistical analysis of rheological data of vocal fold tissues, in order to account for the data correlation caused by multiple measurements of each tissue sample across the test frequency range. Such data correlation had often been overlooked in previous studies in the past decades. The viscoelastic shear properties of the vocal fold lamina propria of two commonly used laryngeal research animal species (i.e. rabbit, porcine) were measured by a linear, controlled-strain simple-shear rheometer. Along with published canine and human rheological data, the vocal fold viscoelastic shear moduli of these animal species were compared to those of human over a frequency range of 1-250Hz using the mixed-effects models. Our results indicated that tissues of the rabbit, canine and porcine vocal fold lamina propria were significantly stiffer and more viscous than those of human. Mixed-effects models were shown to be able to more accurately analyze rheological data generated from repeated measurements.

Indexed as

AnimalsDogsElasticityHumansModels, StatisticalMucous MembraneRabbitsRheologySwineViscosityVocal CordsAnimal modelMixed-effects modelRheologyStatistical analysisViscoelastic shear propertiesVocal fold

Identifiers

PMID28823902
PMCPMC6486179

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.