ArticleJACC. Cardiovascular imaging2018
Noninvasive Imaging of the Coronary Vasculature Using Ultrafast Ultrasound.
Article in JACC. Cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Assessment of the healing process after percutaneous implantation of a cardiovascular device: a systematic review.The international journal of cardiovascular imaging · 2020Pooled it
- Multimodal non-invasive ultrasound for predicting severe coronary artery stenosis in right coronary dominant patients.BMC cardiovascular disorders · 2026Observational
- High-Frame-Rate Echocardiography: A New Frontier in Noninvasive Functional Assessment.Journal of clinical medicine · 2026Review
- Ultrasound in cardiovascular care: a perspective on preventive, diagnostic, and monitoring applications.Frontiers in cardiovascular medicine · 2026Article
- In Vivo Dynamic Coronary Arteries Blood Flow Imaging Based on Multi-Cycle Phase Clustering Ultrafast Ultrasound.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Noninvasive assessment of myocardial perfusion using ultrafast ultrasound: clinical study for congenital heart disease.European heart journal. Imaging methods and practice · 2025Article
- Transthoracic ultrasound localization microscopy of myocardial vasculature in patients.Nature biomedical engineering · 2024Article
- Superharmonic and Microultrasound Imaging With Plane Wave Beamforming Techniques.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Review
- Non-invasive Measurement of the Viscoelasticity of the Optic Nerve and Sclera for Assessing Papilledema: A Pilot Clinical Study.Ultrasound in medicine & biology · 2023Article
- Ultrafast Power Doppler for Detecting Intraoperative Myocardial Perfusion in Infants With Critical Congenital Heart Disease.JACC. Advances · 2023Article
- Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics.Scientific reports · 2022Article
- Grating Lobe Reduction in Plane-Wave Imaging With Angular Compounding Using Subtraction of Coherent Signals.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- A Review of Clinical Applications for Super-resolution Ultrasound Localization Microscopy.Current medical science · 2022Review
- Emerging methods for the characterization of ischemic heart disease: ultrafast Doppler angiography, micro-CT, photon-counting CT, novel MRI and PET techniques, and artificial intelligence.European radiology experimental · 2021Review
- Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia.Nature reviews. Cardiology · 2020Article
- The New Wave of Cardiovascular Biomechanics.JACC. Cardiovascular imaging · 2019Article
- EXPRESS: Right Heart in Pulmonary Hypertension: From Adaptation to Failure.Pulmonary circulation · 2019Article
- Preclinical Imaging Biomarkers for Postischaemic Neurovascular Remodelling.Contrast media & molecular imaging · 2019Review
- Multi-parametric functional ultrasound imaging of cerebral hemodynamics in a cardiopulmonary resuscitation model.Scientific reports · 2018Article
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8 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesThe aim of this study was to investigate the potential of coronary ultrafast Doppler angiography (CUDA), a novel vascular imaging technique based on ultrafast ultrasound, to image noninvasively with high sensitivity the intramyocardial coronary vasculature and quantify the coronary blood flow dynamics.
backgroundNoninvasive coronary imaging techniques are currently limited to the observation of the epicardial coronary arteries. However, many studies have highlighted the importance of the coronary microcirculation and microvascular disease.
methodsCUDA was performed in vivo in open-chest procedures in 9 swine. Ultrafast plane-wave imaging at 2,000 frames/s was combined to an adaptive spatiotemporal filtering to achieve ultrahigh-sensitive imaging of the coronary blood flows. Quantification of the flow change was performed during hyperemia after a 30-s left anterior descending (LAD) artery occlusion followed by reperfusion and was compared to gold standard measurements provided by a flowmeter probe placed at a proximal location on the LAD (n = 5). Coronary flow reserve was assessed during intravenous perfusion of adenosine. Vascular damages were evaluated during a second set of experiments in which the LAD was occluded for 90 min, followed by 150 min of reperfusion to induce myocardial infarction (n = 3). Finally, the transthoracic feasibility of CUDA was assessed on 2 adult and 2 pediatric volunteers.
resultsUltrahigh-sensitive cine loops of venous and arterial intramyocardial blood flows were obtained within 1 cardiac cycle. Quantification of the coronary flow changes during hyperemia was in good agreement with gold standard measurements (r
conclusionsUltrafast Doppler imaging can map the coronary vasculature with high sensitivity and quantify intramural coronary blood flow changes.
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