Evidence map›Paper›PMID 28823678›Full record

ArticleCurrent biology : CB2017

A Single Set of Interneurons Drives Opposite Behaviors in C. elegans.

Manon L Guillermin, Mayra A Carrillo, Elissa A Hallem

Open access · bronzeAbstract read
In one paragraph

Article in Current biology : CB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  7. Outcrossing inEcology and evolution · 2024
    Article
  8. Article
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  10. Differential processing of a chemosensory cue across life stages sharing the same valence state inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Review
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  16. Review
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  19. Context-dependent operation of neural circuits underlies a navigation behavior inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Presynaptic MAST kinase controls opposing postsynaptic responses to convey stimulus valence inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Manon L GuillerminDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Mayra A CarrilloDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: ehallem@ucla.edu.
University of California, Los Angeles · US

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
NIGMS NIH HHS T32 GM007185
6 · The paper itself

Abstract

Many chemosensory stimuli evoke innate behavioral responses that can be either appetitive or aversive, depending on an animal's age, prior experience, nutritional status, and environment [1-9]. However, the circuit mechanisms that enable these valence changes are poorly understood. Here, we show that Caenorhabditis elegans can alternate between attractive or aversive responses to carbon dioxide (CO

Indexed as

ChemotaxisAnimalsCaenorhabditis elegansCarbon DioxideInterneuronsCarbon Dioxidecarbon dioxide responseC. eleganschemosensationexperience-dependent modulationgas sensingneuromodulationolfactory behaviorsensory valence

Identifiers

PMID28823678
PMCPMC6193758
OpenAlexW2747188128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.