ArticleJournal of theoretical biology2017
Heterogeneity in schistosomiasis transmission dynamics.
Article in Journal of theoretical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Prevalence and correlations of schistosomiasis mansoni and schistosomiasis haematobium among humans and intermediate snail hosts: a systematic review and meta-analysis.Infectious diseases of poverty · 2024Pooled it
- Extensive parasite transmission and variation in a functional receptor associated with drug resistance in endemicScience advances · 2026Article
- Pharos: a mobile GIS application for network assessment and ground-truth mapping to support mHealth study design in low-resource settings.International journal of geographical information science : IJGIS · 2026Article
- Vaccine value profile for schistosomiasis.Vaccine · 2025Article
- Population-level impact of mass drug administration against schistosomiasis with anthelmintic drugs targeting juvenile schistosomes: a modelling study.The Lancet. Microbe · 2025Article
- A comparative analysis of the prevalence and intensity of schistosomiasis and soil-transmitted helminth infections between preschool-aged children and school-going children in KwaZulu-Natal Province.Parasitology research · 2025Article
- Spatiotemporal analysis of schistosomiasis and soil-transmitted helminth distribution in three highly endemic provinces in Angola.PLoS neglected tropical diseases · 2025Article
- Seasonal distribution and cercarial shedding ofCurrent research in parasitology & vector-borne diseases · 2025Article
- Getting into host's skin: initial immune response toFrontiers in immunology · 2025Review
- Schistosomiasis transmission: A machine learning analysis reveals the importance of agrochemicals on snail abundance in Rwanda.PLoS neglected tropical diseases · 2024Article
- Development of prediction models to identify hotspots of schistosomiasis in endemic regions to guide mass drug administration.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Enabling targeted mass drug administration for schistosomiasis in north-western Tanzania: Exploring the use of geostatistical modeling to inform planning at sub-district level.PLoS neglected tropical diseases · 2024Article
- Identifying determinants for the seropositive rate of schistosomiasis in Hunan province, China: A multi-scale geographically weighted regression model.PLoS neglected tropical diseases · 2023Article
- Prevalence of Intestinal Parasitosis in Guinea: Systematic Review of the Literature and Meta-Analysis.Pathogens (Basel, Switzerland) · 2023Review
- Schistosoma Transmission in a Dynamic Seasonal Environment and its Impact on the Effectiveness of Disease Control.The Journal of infectious diseases · 2022Article
- Article
- Exposure, hazard, and vulnerability all contribute to Schistosoma haematobium re-infection in northern Senegal.PLoS neglected tropical diseases · 2021Article
- Discovering environmental management opportunities for infectious disease control.Scientific reports · 2021Article
- Impact of seven years of mass drug administration and recrudescence of Schistosoma haematobium infections after one year of treatment gap in Zanzibar: Repeated cross-sectional studies.PLoS neglected tropical diseases · 2021Article
- Schistosomiasis Morbidity Hotspots: Roles of the Human Host, the Parasite and Their Interface in the Development of Severe Morbidity.Frontiers in immunology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
Simple models of disease propagation often disregard the effects of transmission heterogeneity on the ecological and epidemiological dynamics associated with host-parasite interactions. However, for some diseases like schistosomiasis, a widespread parasitic infection caused by Schistosoma worms, accounting for heterogeneity is crucial to both characterize long-term dynamics and evaluate opportunities for disease control. Elaborating on the classic Macdonald model for macroparasite transmission, we analyze families of models including explicit descriptions of heterogeneity related to differential transmission risk within a community, water contact patterns, the distribution of the snail host population, human mobility, and the seasonal fluctuations of the environment. Through simple numerical examples, we show that heterogeneous multigroup communities may be more prone to schistosomiasis than homogeneous ones, that the availability of multiple water sources can hinder parasite transmission, and that both spatial and temporal heterogeneities may have nontrivial implications for disease endemicity. Finally, we discuss the implications of heterogeneity for disease control. Although focused on schistosomiasis, results from this study may apply as well to other parasitic infections with complex transmission cycles, such as cysticercosis, dracunculiasis and fasciolosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.