Evidence map›Paper›PMID 28823151›Full record

ArticleBiochemistry2017

CmlI N-Oxygenase Catalyzes the Final Three Steps in Chloramphenicol Biosynthesis without Dissociation of Intermediates.

Anna J Komor, Brent S Rivard, Ruixi Fan, Yisong Guo, Lawrence Que, John D Lipscomb

Open access · greenAbstract readComparative Study
In one paragraph

Article in Biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Heme oxygenase-like dimetal oxidases and oxygenases.Biochemical Society transactions · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of theProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. A Peroxodiiron(III/III) Intermediate Mediating BothJournal of the American Chemical Society · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brent S Rivard
Ruixi FanDepartment of Chemistry, Carnegie Mellon University , Pittsburgh, Pennsylvania 15213, United States.
Yisong GuoDepartment of Chemistry, Carnegie Mellon University , Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0002-4132-3565
Carnegie Mellon University · USUniversity of Minnesota · US

Funding

Synthetic Models and Spectroscopy of Nonheme Diiron EnzymesR01GM038767 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI QUE, LAWRENCE · 1987 to 2018
$5.8M
Chemistry-Biology Interface Training GrantT32GM008700 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DISTEFANO, MARK D · 1999 to 2018
$4.0M
Intermediates in O2 Activation by Oxygenases at Non-heme Iron CentersR35GM118030 · NIGMS · UNIVERSITY OF MINNESOTA · PI LIPSCOMB, JOHN D · 2016 to 2020
$2.7M
NIGMS NIH HHS R01 GM038767NIGMS NIH HHS R35 GM118030NIGMS NIH HHS T32 GM008700
6 · The paper itself

Abstract

CmlI catalyzes the six-electron oxidation of an aryl-amine precursor (NH

Indexed as

Models, MolecularAnti-Bacterial AgentsBacterial ProteinsBiocatalysisCatalytic DomainChloramphenicolHalf-LifeKineticsNonheme Iron ProteinsOxidation-ReductionOxygenOxygenasesSpectroscopy, MossbauerStreptomycesAnti-Bacterial AgentsBacterial ProteinsChloramphenicolNonheme Iron ProteinsOxygenOxygenases

Identifiers

PMID28823151
PMCPMC5605456
OpenAlexW2748821064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.