Evidence map›Paper›PMID 28823105›Full record

ReviewCurrent psychiatry reports2017

Understanding Peripartum Depression Through Neuroimaging: a Review of Structural and Functional Connectivity and Molecular Imaging Research.

Christy Duan, Jessica Cosgrove, Kristina M Deligiannidis

Abstract readReview
In one paragraph

Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Stress and parental behaviors.Neuroscience research · 2025
    Review
  9. Biomarkers of reproductive psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2025
    Review
  10. Review
  11. Article
  12. Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.European psychiatry : the journal of the Association of European Psychiatrists · 2024
    Article
  13. Novel neurosteroid therapeutics for post-partum depression: perspectives on clinical trials, program development, active research, and future directions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  14. Review
  15. Article
  16. Recent Neuroscience Advances in Human Parenting.Advances in neurobiology · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Neurobiology of peripartum mental illness.Handbook of clinical neurology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christy DuanDepartment of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York City, NY, 11004, USA.
Jessica CosgroveDepartment of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York City, NY, 11004, USA.
Kristina M DeligiannidisWomen's Behavioral Health, Zucker Hillside Hospital, Northwell Health, 75-59 263rd Street, Glen Oaks, New York City, NY, 11004, USA. kdeligian1@northwell.edu.
Northwell Health · USZucker Hillside Hospital · US

Funding

Neuroendocrine and Neuroimaging Endophenotypes in Postpartum DepressionK23MH097794 · NIMH · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DELIGIANNIDIS, KRISTINA MARIE · 2013 to 2017
$897k
NIMH NIH HHS K23 MH097794NIMH NIH HHS L30 MH104713
6 · The paper itself

Abstract

purpose of reviewImaging research has sought to uncover brain structure, function, and metabolism in women with postpartum depression (PPD) as little is known about its underlying pathophysiology. This review discusses the imaging modalities used to date to evaluate postpartum depression and highlights recent findings. RECENT

findingsAltered functional connectivity and activity changes in brain areas implicated in executive functioning and emotion and reward processing have been identified in PPD. Metabolism changes involving monoamine oxidase A, gamma-aminobutyric acid, glutamate, serotonin, and dopamine have additionally been reported. To date, no studies have evaluated gray matter morphometry, voxel-based morphometry, surface area, cortical thickness, or white matter tract integrity in PPD. Recent imaging studies report changes in functional connectivity and metabolism in women with PPD vs. healthy comparison women. Future research is needed to extend these findings as they have important implications for the prevention and treatment of postpartum mood disorders.

Indexed as

BrainDepression, PostpartumFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMolecular ImagingNeuroimagingPeripartum PeriodPositron-Emission TomographyDepressionMagnetic resonance imagingNeuroimagingPerinatalPostpartum

Identifiers

PMID28823105
PMCPMC5617352
OpenAlexW2746169007

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.