SynthesisObesity surgery2018
Single Anastomosis Duodeno-Ileal Switch (SADIS): A Systematic Review of Efficacy and Safety.
Synthesis in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 9 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- SADI-S, state of the art. Indications and results in 2024: a systematic review of literature.Updates in surgery · 2025Pooled it
- Five-Year Outcomes of Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy: A Systematic Review.Obesity surgery · 2025Pooled it
- Therapeutic Options for Recurrence of Weight and Obesity Related Complications After Metabolic and Bariatric Surgery: An IFSO Position Statement.Obesity surgery · 2024Guideline
- The Efficacy and Safety of Laparoscopic Single-Anastomosis Duodeno-ileostomy with Sleeve Gastrectomy (SADI-S) in Mid- and Long-Term Follow-Up: a Systematic Review.Obesity surgery · 2023Pooled it
- Bile Reflux After Single Anastomosis Duodenal-Ileal Bypass with Sleeve (SADI-S): a Meta-analysis of 2,029 Patients.Obesity surgery · 2022Pooled it
- Evaluation of Metabolic Outcomes Following SADI-S: a Systematic Review and Meta-analysis.Obesity surgery · 2022Pooled it
- The Effectiveness of Single-Anastomosis Duodenoileal Bypass with Sleeve Gastrectomy/One Anastomosis Duodenal Switch (SADI-S/OADS): an Updated Systematic Review.Obesity surgery · 2021Pooled it
- Diagnostic and Therapeutic Management of Post-Gastric Bypass Chronic Diarrhea: a Systematic Review.Obesity surgery · 2020Pooled it
- Robotic Single Anastomosis Duodenal-ileal Bypass With Sleeve Gastrectomy (SADI-S) for Morbid Obesity: A Systematic Review.In vivo (Athens, Greece)Pooled it
- Perioperative Safety and 1-Year Outcomes of Single-Anastomosis Duodeno-Ileal Bypass (SADI) vs. Biliopancreatic Diversion with Duodenal Switch (BPD/DS): A Randomized Clinical Trial.Obesity surgery · 2024Trial
- Long Alimentary Limb Duodenal Switch (LADS): an Exploratory Randomized Trial, Results at 2 Years.Obesity surgery · 2020Trial
- Six-month weight loss and comorbidity remission after sleeve gastrectomy, Roux-en-Y gastric bypass, BPD-DS, and SADI-S: propensity score analysis using the 2023 MBSAQIP database.Surgical endoscopy · 2026Article
- Five-year outcomes of two duodenal switch variants: BPD/DS vs. SADI-S.Surgical endoscopy · 2026Article
- Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy Prevents Atherosclerosis Development in LDL Receptor Deficient Mice.Obesity surgery · 2026Article
- One Anastomosis Gastric Bypass Versus Single Anastomosis Sleeve Jejunal Bypass: Does Duodenal Exclusion Matter?Obesity surgery · 2026Review
- Recent Advances in Metabolic and Bariatric Surgery: A Narrative Review of Therapeutic Strategies for Weight Loss and Metabolic Health.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Review
- One-Year Outcomes of SADI-S in Chinese Patients with Type 2 Diabetes and BMI < 35 kg/mObesity surgery · 2025Article
- Pre-Operative Gastroesophageal Reflux Does Not Affect 30-Day Outcomes in Patients Undergoing Revisional Bariatric Surgery to Single Anastomosis Duodeno-Ileal Bypass (SADI): An Analysis of 933 Metabolic and Bariatric Accreditation and Quality Improvement Program Patients.Journal of clinical medicine · 2024Article
- Nutritional Challenges and Treatment After Bariatric Surgery.Annual review of nutrition · 2024Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOwing to the possibility of weight regain after the long-term follow-up of gastric bypass patients and because of the high morbidity of biliopancreatic diversion with duodenal switch, single-anastomosis duodeno-ileal switch (SADIS) has emerged as a rescue procedure in bariatric surgery.
objectiveThe purpose of this review is to summarize the literature data on SADIS.
settingUniversity Hospital, NY.
methodsA comprehensive literature review was performed through October 2016 to identify English studies on SADIS performed in human subjects. Outcomes of interest were technical considerations, postoperative complications, weight loss outcome, comorbidity resolution rate, and nutritional deficiency after SADIS.
resultsA total of 12 studies including 581 SADIS patients (217 males and 364 females) were included. SADIS was a primary procedure in 508 patients (87.4%) and a conversion procedure in 73 patients (12.6%). The length of common limb was 300 cm in 54.2%, 250 cm in 23%, and 200 cm in 13.4% of patients. Anastomosis technique was a linear stapler in 26.7% and a hand sewn suture technique in 73.3% of patients. Diarrhea was the most common complication (1.2%). The average %EWL was 30% at 3 months, 55% at 6 months, 70% at 1 year, and 85% at 2 years. Co-morbidity resolution rate was 74.1% for type 2 diabetes mellitus, 96.3% for hypertension, 68.3% for dyslipidemia, 63.3% for obstructive sleep apnea, and 87.5% for GERD. Overall, vitamin A, selenium, and iron deficiency were the most common nutritional deficiencies with the possibility of the protein malnutrition in up to 34% of the patients when measured.
conclusionAs a modified bariatric procedure, SADIS has promising outcomes for weight loss and comorbidity resolution in morbidly obese patients. When measured, there was a high prevalence of macro-nutrient deficiencies following SADIS. There is a high technical variability, and long-term data are required before any meaningful conclusion can be made.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.