Evidence map›Paper›PMID 28823062›Full record

SynthesisGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017

Treatment of retinal artery occlusion using transluminal Nd:YAG laser: a systematic review and meta-analysis.

Vitaly Man, Idan Hecht, Michal Talitman, Assaf Hilely, Mohamad Midlij, Zvia Burgansky-Eliash, Asaf Achiron

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Antithrombotic use in retinal artery occlusion: A narrative review.The Kaohsiung journal of medical sciences · 2025
    Review
  6. Early prostaglandin EFrontiers in ophthalmology · 2025
    Article
  7. Article
  8. Review
  9. The role of cholesterol crystals and ocular crystal emboli in retinal pathology.American heart journal plus : cardiology research and practice · 2024
    Article
  10. Review
  11. Article
  12. Progress in central retinal artery occlusion: a narrative review.The Journal of international medical research · 2023
    Review
  13. Article
  14. Intra-Arterial Thrombolysis for Central Retinal Artery Occlusion.Clinical ophthalmology (Auckland, N.Z.) · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vitaly ManDepartment of Ophthalmology, Soroka University Medical Center, Beer Sheva, Israel.
Idan HechtDepartment of Ophthalmology, Soroka University Medical Center, Beer Sheva, Israel. idanhe@gmail.com.ORCID http://orcid.org/0000-0001-5634-0432
Michal TalitmanDepartment of Statistics and Operation Research, Tel-Aviv University, Tel Aviv, Israel.
Assaf HilelyThe Hebrew University of Jerusalem, Jerusalem, Israel.
Mohamad MidlijSackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Zvia Burgansky-EliashSackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Asaf AchironSackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Tel Aviv University · ILBen-Gurion University of the Negev · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo review clinical experience, efficacy, and safety of transluminal Nd:YAG laser embolectomy/embolysis (TYE) for retinal artery occlusion.

methodsElectronic databases were searched for all published clinical studies and case-reports reporting on TYE in central (CRAO) or branch (BRAO) retinal artery occlusion. Individual patient data was evaluated in a weighted pooled analysis.

resultsSixty-one cases were reported, 47 with BRAO and 14 with CRAO. Visual acuity (VA) at onset averaged 20/252 (1.1 LogMAR) and improved following the procedure to 20/47 (0.37 LogMAR) at first follow-up (avg. 6 days, P < 0.001) and to 20/30 (0.18 LogMAR) at last reported follow-up (avg. 1.1 years, P = 0.02). Patients with worse VA (<20/200) improved further (12 vs. three lines, P < 0.001). VA was not improved when using higher pulse energies (≥ 2.4 mJ) which were associated with more vitrectomies. In a weighted analysis vitreous/sub-retinal hemorrhage was estimated to occur in 54% of cases and required vitrectomy in 18% of cases.

conclusionsTYE was followed by significant visual improvement in the vast majority of cases, including CRAO, and was frequently associated with vitreous hemorrhage. Patients with poor visual acuity appear to benefit further and higher pulse energies may be detrimental. Lack of randomization and intrinsic biases prevent any definite conclusions regarding the benefits and further research is warranted.

Indexed as

HumansLasers, Solid-StateLaser TherapyRetinal Artery OcclusionBRAOCRAOEmbolectomyEmbolysisNd:YAG laserRetinal artery occlusion

Identifiers

PMID28823062
OpenAlexW2749047105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.