Evidence map›Paper›PMID 28822771›Full record

ArticleExperimental hematology2017

PGE

Terence A McGonigle, Amy R Dwyer, Eloise L Greenland, Naomi M Scott, Kevin N Keane, Philip Newsholme, Helen S Goodridge, Leonard I Zon, Fiona J Pixley, Prue H Hart

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. The Ontogeny of Monocyte Subsets.Frontiers in immunology · 2019
    Review
  2. Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGEArteriosclerosis, thrombosis, and vascular biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Terence A McGonigleTelethon Kids Institute, University of Western Australia, West Perth, Western Australia, Australia.
Amy R DwyerSchool of Biomedical Sciences, University of Western Australia, Western Australia, Australia.
Eloise L GreenlandSchool of Biomedical Sciences, University of Western Australia, Western Australia, Australia.
Naomi M ScottTelethon Kids Institute, University of Western Australia, West Perth, Western Australia, Australia.
Kevin N KeaneSchool of Biomedical Sciences, Curtin Health Innovation Research Institute Biosciences, Curtin University, Perth, Australia.
Philip NewsholmeSchool of Biomedical Sciences, Curtin Health Innovation Research Institute Biosciences, Curtin University, Perth, Australia.
Helen S GoodridgeBoard of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
Leonard I ZonStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Harvard Stem Cell Institute, Harvard, Boston, MA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA.
Fiona J PixleySchool of Biomedical Sciences, University of Western Australia, Western Australia, Australia.
Prue H HartTelethon Kids Institute, University of Western Australia, West Perth, Western Australia, Australia. Electronic address: Prue.Hart@telethonkids.org.au.
University of Western Australia · AUCurtin University · AUCedars-Sinai Medical Center · USHoward Hughes Medical Institute · USThe Kids Research Institute Australia · AU

Funding

Customized stem cells for clinical application in blood disordersR24DK092760 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI COLLINS, JAMES J, DALEY, GEORGE Q · 2011 to 2018
$10.7M
Project-002U54DK110805 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI ORKIN, STUART H, ZON, LEONARD IRA · 2016 to 2020
$5.9M
EMBRYONIC HEMATOPOIESISR01HL048801 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI ZON, LEONARD IRA · 1992 to 2016
$5.7M
NHLBI NIH HHS R01 HL048801NIDDK NIH HHS R24 DK092760NIDDK NIH HHS U54 DK110805
6 · The paper itself

Abstract

Monocytes/macrophages differentiating from bone marrow (BM) cells pulsed for 2 hours at 37°C with a stabilized derivative of prostaglandin E

Indexed as

16,16-Dimethylprostaglandin E2AnimalsBone Marrow CellsCell MovementChemokine CCL2DinoprostoneMacrophage Colony-Stimulating FactorMacrophagesMiceMonocytes16,16-Dimethylprostaglandin E2Ccl2 protein, mouseChemokine CCL2DinoprostoneMacrophage Colony-Stimulating Factor

Identifiers

PMID28822771
PMCPMC5972521
OpenAlexW2748376953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.