Evidence map›Paper›PMID 28822508›Full record

ArticleIndian heart journal

Prevalence and characteristics of resistant hypertensive patients in an Asian population.

Rabia Naseem, Arsalan Majeed Adam, Fiza Khan, Adiya Dossal, Ibrahim Khan, Ammara Khan, Hannah Paul, Hafsa Jawed, Aisha Aslam, Faez Muhammad Syed and 5 more

Open access · goldAbstract read
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Management of Hypertension in the Asia-Pacific Region: A Structured Review.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. The Burden of Resistant Hypertension Across the World.Current hypertension reports · 2022
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Rabia NaseemDow Medical College, Dow University of Health Sciences, Karachi, Pakistan. Electronic address: rabianaseemm@gmail.com.
Arsalan Majeed AdamDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Fiza KhanJinnah Sindh Medical University, Karachi, Pakistan.
Adiya DossalJinnah Sindh Medical University, Karachi, Pakistan.
Ibrahim KhanDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Ammara KhanDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Hannah PaulJinnah Sindh Medical University, Karachi, Pakistan.
Hafsa JawedDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Aisha AslamDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Faez Muhammad SyedDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Muhammad Ahsen NiaziDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Shehzeen NadeemZiauddin University, Karachi, Pakistan.
Aruba KhanJinnah Sindh Medical University, Karachi, Pakistan.
Amber ZiaDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Mohammad Hussham ArshadDepartment of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Dow University of Health Sciences · PKJinnah Sindh Medical University · PKAga Khan University Hospital · PKZiauddin University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistant hypertension is a well-recognized clinical challenge yet there are no reported data on its prevalence in Pakistan. These patients are subjected to a higher risk of developing hypertensive complications. The objective of our study was to evaluate the prevalence and determinants of resistant hypertension in an Asian cohort of hypertensive patients.

methodsThis cross-sectional study was carried out among hypertensive patients visiting a tertiary care hospital in Karachi from September-December 2015. Patient data and characteristics were recorded using a pre-coded questionnaire. Morisky and Berlin questionnaires were used to assess compliance to medications and determine the risk of developing obstructive sleep apnea, respectively. Pearson's chi-square test was used to analyze statistical differences between hypertensive patients and related factors.

resultsA total of 515 patients were included in the study. Overall, 12% of the total patients (n=62) were resistant hypertensives and 25% (n=129) had pseudo-resistant hypertension. Resistant patients were more often females, older and had a higher body mass index (all P<0.001). Use of painkillers and noncompliance to dietary recommendations were found to be significant determinants of resistant hypertension. Prevalence of comorbid conditions, including diabetes (p=0.33), hyperlipidemia (p=0.46), and chronic kidney disease (p=0.23), was not significantly higher in patients with resistant hypertension.

conclusionNearly one in ten hypertensive patients had true resistant hypertension, and twenty-five percent of patients had pseudo-resistance. Resistance hypertensions is significantly associated with female gender, older age, obesity, dietary noncompliance and increased use of NSAIDs.

Indexed as

Blood PressureCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedPakistanPrevalenceRetrospective StudiesRisk FactorsPakistanPrevalenceResistant hypertension

Identifiers

PMID28822508
PMCPMC5560875
OpenAlexW2582874147

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.