Evidence map›Paper›PMID 28822352›Full record

ArticleJournal of biomedical science2017

Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages.

Chun-Liang Chen, Shu-Chun Chien, Tzeng-Horng Leu, Hans I-Chen Harn, Ming-Jer Tang, Lien-I Hor

Open access · diamondAbstract read
In one paragraph

Article in Journal of biomedical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Comparative Transcriptomic Analysis Underlies the Differential Virulence ofInternational journal of molecular sciences · 2025
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  3. Article
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  5. Review
  6. Article
  7. Article
  8. TheScience signaling · 2020
    Article
  9. The Role of TSC1 in the Macrophages AgainstFrontiers in cellular and infection microbiology · 2020
    Article
  10. Article
  11. Emerging microbes & infections · 2019
    Article
  12. Article
  13. Accessory Toxins ofFrontiers in microbiology · 2018
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chun-Liang ChenDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Shu-Chun ChienDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Tzeng-Horng LeuInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Hans I-Chen HarnInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Ming-Jer TangInstitute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan.
Lien-I HorDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, 70101, Taiwan. h061453@mail.ncku.edu.tw.ORCID http://orcid.org/0000-0002-8252-8380
National Cheng Kung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVibrio vulnificus is a marine bacterial species that causes opportunistic infections manifested by serious skin lesions and fulminant septicemia in humans. We have previously shown that the multifunctional autoprocessing repeats in toxin (MARTX

methodsWe compared between a wild-type V. vulnificus strain and its MARTX

resultsThe RAW 264.7 cells and mouse peritoneal exudate macrophages underwent cell rounding accompanied by F-actin disorganization in the presence of MARTX

conclusionsMARTX

Indexed as

AnimalsBacterial ToxinsCytotoxinsMacrophagesMaleMice, Inbred BALB CPhagocytosisVibrio InfectionsVibrio vulnificusBacterial ToxinsCytotoxinsAntiphagocytosisCell roundingDomain-deletion mutantsMARTXSignaling pathwayVibrio vulnificus

Identifiers

PMID28822352
PMCPMC5563386
OpenAlexW2749508915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.