ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2018
Effect of a patient-specific minimum activity in stress myocardial perfusion imaging using CZT-SPECT: Prognostic value, radiation dose, and scan outcome.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The next step in standardizing SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Effect of reduced photon count levels and choice of normal data on semi-automated image assessment in cardiac SPECT: Doing more with fewer counts.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Dose reduction is good but it is image quality that matters.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Ultra-low-dose computed tomography for attenuation correction of cadmium-zinc-telluride single photon emission computed tomography myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Dose-optimization in nuclear cardiac imaging, time for the next step?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Improving perfusion defect detection with respiratory motion correction in cardiac SPECT at standard and reduced doses.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Dual isotope stress Tl-201 and rest Tc-99m CZT SPECT: Are we truly leveraging CZT technology?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- The prognostic value of ultra low-dose thallium myocardial perfusion protocol using CZT SPECT.The international journal of cardiovascular imaging · 2019Article
- Minimal rest activity for SPECT myocardial perfusion imaging in a one-day stress-first protocol.European journal of nuclear medicine and molecular imaging · 2019Article
- Cardiac motion correction for improving perfusion defect detection in cardiac SPECT at standard and reduced doses of activity.Physics in medicine and biology · 2019Article
- The very hungry caterpillar and the ongoing effort to reduce radiation in myocardial perfusion scintigraphy: Have we become the beautiful butterfly?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Patient-specific activity or scan-time in SPECT myocardial perfusion imaging: A hands-on approach.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSPECT Myocardial perfusion imaging (MPI) is associated with a relatively high radiation burden and decreasing image quality in heavy patients. Patient-specific low-activity protocols (PLAPs) are suggested but follow-up data is lacking. Our aim was to compare the use of a standard fixed-activity protocol (FAP) with a PLAP in cadmium zinc telluride (CZT)-SPECT MPI.
methodsWe retrospectively included 1255 consecutive patients who underwent CZT-SPECT stress-optional rest MPI. 668 Patients were scanned using FAP (370 MBq) and 587 patients using PLAP (2.25 MBq·kg
resultsThe percentage of scans interpreted as normal was 67% in FAP and 70% in PLAP groups (P = .29). The annualized hard event rates in these patients were 1.0% in the FAP and 0.9% in the PLAP group (P = .86). However, the mean radiation dose decreased by 23% for stress-only and by 15% to 2.6 mSv for stress-optional rest MPI after introduction of the PLAP (p<0.001).
conclusionsIntroduction of a patient-specific low-activity protocol does not affect the percentage of scans interpreted as normal or prognosis but significantly lowers the radiation dose for CZT-SPECT MPI.
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