Evidence map›Paper›PMID 28821967›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2018

Effects of oxytocin and arginine vasopressin on the proliferation and differentiation of a serotonergic cell line.

Zoya Marinova, Susanne Walitza, Edna Grünblatt

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Zoya MarinovaDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zürich, Wagistrasse 12, 8952, Schlieren, Switzerland. Zoya.Marinova@barmelweid.ch.
Susanne WalitzaDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zürich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Edna GrünblattDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zürich, Wagistrasse 12, 8952, Schlieren, Switzerland. edna.gruenblatt@kjpd.uzh.ch.
ETH Zurich · CHUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 134106
6 · The paper itself

Abstract

The neuropeptides oxytocin and arginine vasopressin (AVP) are involved in the regulation of social behavior and cognition. The current study analyzed the effect of oxytocin and AVP on proliferation and differentiation of serotonergic neurons (RN46A cells). Oxytocin did not affect, while 5-10 μM AVP decreased RN46A proliferation. Oxytocin did not significantly alter, while 10 μM AVP decreased the number of cells extending neurites. We found divergent effects of oxytocin and AVP in serotonergic neurons, underscoring their functional differences.

Indexed as

AnimalsArginine VasopressinCell DifferentiationCell LineCell ProliferationDose-Response Relationship, DrugOxytocinRatsSerotonergic NeuronsArginine VasopressinOxytocinArginine vasopressinCell proliferationNeuronal differentiationOxytocinSerotonergic neurons

Identifiers

PMID28821967
OpenAlexW2747619183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.