ArticleJournal of neurology2017
Midlife work-related stress is associated with late-life cognition.
Article in Journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed.
- Trajectories of late-life job insecurity and labor force participation: Associations with cognitive function and impairment in the Health and Retirement Study's harmonized cognitive assessment protocol.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Review
- Midlife financial stress and cognitive and physical impairments in older age: The role of potentially modifying factors.Social science & medicine (1982) · 2025Article
- Midlife stress-related exhaustion and dementia incidence: a longitudinal study over 50 years in women.BMC psychiatry · 2024Article
- Article
- Impact of early work start on mental health outcomes in older adults: A cross-sectional study from Ecuador.PloS one · 2024Article
- Adherence to the Mediterranean diet and waist-to-hip ratio in middle-aged postmenopausal women are the main factors associated with semantic verbal fluency 12 years later.Frontiers in nutrition · 2023Article
- Correlates of Memory and Executive Function in Middle-Aged and Older Adults in the CLSA: A Minority Stress Approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Impact of chronic stress exposure on cognitive performance incorporating the active and healthy aging (AHA) concept within the cross-sectional Bern Cohort Study 2014 (BeCS-14).Archives of gynecology and obstetrics · 2022Observational
- Stress and Turnover Intentions Within Healthcare Teams: The Mediating Role of Psychological Safety, and the Moderating Effect of COVID-19 Worry and Supervisor Support.Frontiers in psychology · 2021Article
- Intensified Job Demands and Cognitive Stress Symptoms: The Moderator Role of Individual Characteristics.Frontiers in psychology · 2021Article
- Occupational Physical Stress Is Negatively Associated With Hippocampal Volume and Memory in Older Adults.Frontiers in human neuroscience · 2020Article
- Emerging Issues in Occupational Disease: Mental Health in the Aging Working Population and Cognitive Impairment-A Narrative Review.BioMed research international · 2020Review
- Inhibiting RIP1 Improves Chronic Stress-Induced Cognitive Impairments in D-Galactose-Induced Aging Mice.Frontiers in behavioral neuroscience · 2018Article
- Do Effort and Reward at Work Predict Changes in Cognitive Function? First Longitudinal Results from the Representative German Socio-Economic Panel.International journal of environmental research and public health · 2017Article
- Article
- Stressors in Midlife and Risk of Dementia: The Role of Race and Education.Alzheimer disease and associated disordersArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the associations between midlife work-related stress and late-life cognition in individuals without dementia from the general population. The Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study population (n = 2000) was randomly selected from independent Finnish population-based surveys (baseline mean age 50 years). Participants underwent two re-examinations in late life (mean age 71 and 78 years, respectively). 1511 subjects participated in at least one re-examination (mean total follow-up 25 years). Work-related stress was measured using two questions on work demands administered in midlife. Multiple cognitive domains were assessed. Analyses were adjusted for several potential confounders. Higher levels of midlife work-related stress were associated with poorer performance on global cognition [β-coefficient, -0.02; 95% confidence interval (CI), -0.05 to -0.00], and processing speed [β -0.03, CI -0.05 to -0.01]. Results remained significant after adjusting for potential confounders. Work-related stress was not significantly associated with episodic memory, executive functioning, verbal fluency or manual dexterity. This study shows that global cognition and processing speed may be particularly susceptible to the effects of midlife work-related stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.