Evidence map›Paper›PMID 28821920›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

TSPO PET for glioma imaging using the novel ligand

Nathalie L Albert, M Unterrainer, D F Fleischmann, S Lindner, F Vettermann, A Brunegraf, L Vomacka, M Brendel, V Wenter, C Wetzel and 5 more

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  7. Review
  8. Spatio-Temporal Dynamics of MBulletin of mathematical biology · 2025
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  17. Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  18. Article
  19. Article
  20. Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Nathalie L AlbertDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. Nathalie.Albert@med.uni-muenchen.de.
M UnterrainerDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
D F FleischmannGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
S LindnerDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
F VettermannDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
A BrunegrafDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
L VomackaDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
M BrendelDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
V WenterDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
C WetzelDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
R RupprechtDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
J-C TonnGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
C BelkaGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
P BartensteinDepartment of Nuclear Medicine, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
M NiyaziGerman Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DEDeutschen Konsortium für Translationale Krebsforschung · DEUniversity of Regensburg · DE

Funding

Friedrich-Baur-Stiftung 68-17
6 · The paper itself

Abstract

objectiveThe 18-kDa mitochondrial translocator protein (TSPO) was reported to be upregulated in gliomas.

methodsEleven patients with histologically confirmed IDH wildtype gliomas (10 glioblastomas, 1 anaplastic astrocytoma) underwent

resultsAll gliomas were positive on

conclusion

Indexed as

CarbazolesPositron-Emission TomographyFemaleGlioblastomaHumansLigandsMaleMiddle AgedPilot ProjectsReceptors, GABARecurrenceCarbazolesGE-180LigandsReceptors, GABATSPO protein, human18F-GE-180GliomaRadiotherapy planningTSPO PET

Identifiers

PMID28821920
OpenAlexW2747879651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.