Evidence map›Paper›PMID 28821869›Full record

ArticleScientific reports2017

TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg

Silvia Ferioli, Susanna Zierler, Joanna Zaißerer, Johann Schredelseker, Thomas Gudermann, Vladimir Chubanov

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 80 citations in OpenAlex.

  1. Renal TRPM6 but not Kv1.1 is required for magnesium homeostasis in mice.American journal of physiology. Renal physiology · 2026
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  13. The Molecular Biology of Placental Transport of Calcium to the Human Foetus.International journal of molecular sciences · 2025
    Review
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  15. Article
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  18. Article
  19. TRPM channels in health and disease.Nature reviews. Nephrology · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Silvia FerioliWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Susanna ZierlerWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.ORCID 0000-0002-4684-0385
Joanna ZaißererWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Johann SchredelsekerWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Thomas GudermannWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany. thomas.gudermann@lrz.uni-muenchen.de.
Vladimir ChubanovWalther Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany. vladimir.chubanov@lrz.uni-muenchen.de.ORCID 0000-0002-6042-4193
Ludwig-Maximilians-Universität München · DECentre of Experimental Medicine of the Slovak Academy of Sciences · SKLMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TRPM6 and its homologue TRPM7 are α-kinase-coupled divalent cation-selective channels activated upon reduction of cytosolic levels of Mg

Indexed as

Protein MultimerizationAdenosine TriphosphatasesAnimalsCell LineCytosolGene ExpressionHumansMagnesiumMiceModels, MolecularPermeabilityProtein ConformationProtein Serine-Threonine KinasesTrophoblastsTRPM Cation ChannelsAdenosine TriphosphatasesMagnesiumProtein Serine-Threonine KinasesTRPM6 protein, humanTrpm6 protein, mouseTRPM7 protein, humanTrpm7 protein, mouseTRPM Cation Channels

Identifiers

PMID28821869
PMCPMC5562840
OpenAlexW2749306122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.