Evidence map›Paper›PMID 28821868›Full record

ArticleScientific reports2017

Dysmobility Syndrome and Risk of Mortality for Community-Dwelling Middle-Aged and Older Adults: The Nexus of Aging and Body Composition.

Wei-Ju Lee, Li-Kuo Liu, An-Chun Hwang, Li-Ning Peng, Ming-Hsien Lin, Liang-Kung Chen

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Risk Factors of Developing Dysmobility Syndrome in Elderly Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Defining an international cut-off of two-legged countermovement jump power for sarcopenia and dysmobility syndrome.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  8. Review
  9. Article
  10. Dysmobility Syndrome Independently Increases Fracture Risk in the Osteoporotic Fractures in Men (MrOS) Prospective Cohort Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
    Article
  11. Low peak jump power is associated with elevated odds of dysmobility syndrome in community-dwelling elderly individuals: the Korean Urban Rural Elderly (KURE) study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wei-Ju LeeAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.
Li-Kuo LiuAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.
An-Chun HwangAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.ORCID 0000-0002-2787-4985
Li-Ning PengAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.
Ming-Hsien LinAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan.
Liang-Kung ChenAging and Health Research Center, National Yang Ming University, Taipei City, Taiwan. lkchen2@vghtpe.gov.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysmobility syndrome is a newly proposed concept to comprehensively consider bone-muscle-adiposity as a whole to associate with mortality and other adverse outcomes in the older adults. Little was known in Asian populations since the body composition was highly related to ethnicity. The study aimed to evaluate the association between dysmobility syndrome and mortality and to explore the most optimal operational definition for dysmobility syndrome. The prevalence of dysmobility syndrome was 3.9-10.1% based on different operational definitions of adiposity and skeletal muscle index. Subjects with dysmobility syndrome were older, more often to be women, having higher adiposity, lower lean body mass and bone mineral density. Multivariate Cox proportional hazard model showed that dysmobility and pre-dysmobility syndrome had higher risk of mortality than the robust group (Hazard ratio (HR): 11.3, 95% confidence interval (CI): 1.2-109.1; and HR 8.7, 95% CI 1.1-67.3, respectively). Overall, the modified operational definition of dysmobility syndrome in Asian populations using FNIH-adjusted skeletal muscle mass and waist circumference-defined adiposity may be the most optimal model for mortality prediction. Taking the nexus of body composition as a whole to evaluate the mortality risk of older adults is an important improvement beyond sarcopenia and osteoporosis.

Indexed as

AdiposityAgedAge FactorsBody CompositionFemaleGeriatric AssessmentHumansMaleMiddle AgedMortalityMusculoskeletal DiseasesPrevalenceProportional Hazards ModelsRisk AssessmentSyndrome

Identifiers

PMID28821868
PMCPMC5562709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.