ArticleScientific reports2017
GABA accretion reduces Lsi-1 and Lsi-2 gene expressions and modulates physiological responses in Oryza sativa to provide tolerance towards arsenic.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 71 citations in OpenAlex.
- γ-Aminobutyric Acid Alleviates Cadmium Toxicity and Is Associated with Increased Ascorbate and Glutathione Levels inInternational journal of molecular sciences · 2026Article
- GABA Mediates the Enhancement of Maize (Microorganisms · 2026Article
- Biochar and γ-Aminobutyric acid partnership improves rice productivity and mitigates Sb + Pb toxicity in co-contaminated soil.BMC plant biology · 2025Article
- Article
- Amino Acid Regulation in Rice: Integrated Mechanisms and Agricultural Applications.Rice (New York, N.Y.) · 2025Review
- Effect of Exogenous γ-Aminobutyric Acid (GABA) on the Growth, Photosynthetic Pigment, Antioxidant and GABA Metabolism ofPlants (Basel, Switzerland) · 2025Article
- Gamma-aminobutyric acid interactions with phytohormones and its role in modulating abiotic and biotic stress in plants.Stress biology · 2024Review
- Exogenous GABA Enhances Copper Stress Resilience in Rice Plants via Antioxidant Defense Mechanisms, Gene Regulation, Mineral Uptake, and Copper Homeostasis.Antioxidants (Basel, Switzerland) · 2024Article
- Review
- Truncation of the calmodulin binding domain in rice glutamate decarboxylase 4 (Molecular breeding : new strategies in plant improvement · 2024Article
- The Molecular Mechanism of the Response of Rice to Arsenic Stress and Effective Strategies to Reduce the Accumulation of Arsenic in Grain.International journal of molecular sciences · 2024Review
- Exogenous γ-aminobutyric acid and Bacillus pumilus reduce arsenic uptake and toxicity in rice.Environmental science and pollution research international · 2024Article
- Gamma-aminobutyric acid treatment promotes resistance againstFrontiers in plant science · 2024Article
- A Biostimulant Based on Silicon Chelates Enhances Growth and Modulates Physiological Responses of In-Vitro-Derived Strawberry Plants to In Vivo Conditions.Plants (Basel, Switzerland) · 2023Article
- Dynamics of Humic Acid, Silicon, and Biochar under Heavy Metal, Drought, and Salinity with Special Reference to Phytohormones, Antioxidants, and Melatonin Synthesis in Rice.International journal of molecular sciences · 2023Article
- Investigation into the Relationship between Spermidine Degradation and Phenolic Compounds Biosynthesis in Barley Seedlings under Ultraviolet B Stress.Plants (Basel, Switzerland) · 2023Article
- Comparison of Silicon-Evoked Responses on Arsenic Stress between Different Dular Rice Genotypes.Plants (Basel, Switzerland) · 2021Article
- Emerging Roles of γ Aminobutyric Acid (GABA) Gated Channels in Plant Stress Tolerance.Plants (Basel, Switzerland) · 2021Review
- γ-Aminobutyrate (GABA) Regulated Plant Defense: Mechanisms and Opportunities.Plants (Basel, Switzerland) · 2021Review
- Alterations of Endogenous Hormones, Antioxidant Metabolism, and Aquaporin Gene Expression in Relation to γ-Aminobutyric Acid-Regulated Thermotolerance in White Clover.Antioxidants (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
GABA counteracts wide range of stresses through regulation of GABA shunt pathway in plants. Although, GABA assisted tolerance against As toxicity in plants is still unexplored. We have examined GABA induced tolerance in rice seedlings with two exposure periods of GABA i.e., short term and long term. Results showed that accumulation of GABA reduced the expressions of Lsi-1 and Lsi-2 transporter genes, which ultimately decreased the accumulation of As in rice seedlings. The accumulation of GABA also modulated the gene expression of GABA shunt pathway and activity of antioxidant enzymes, which strongly induced the tolerance in plants. Antioxidant enzymes such as CAT, POD, GPX and SOD showed maximum alteration in activity with GABA accretion. In both exposure periods, long term accumulation of GABA was highly efficient to provide tolerance to plants against As(III), while higher level of GABA at short term was toxic. Tolerance responses of GABA towards As(III) was reflected by minimal changes in various physiological (WUE, A, gs, PhiPS2, qp, NPQ, ETR and Trmmol) and growth parameters with concomitant accumulation. Oxidative stress marker such as TBARS and H
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