SynthesisScientific reports2017
Neuromodulatory circuit effects on Drosophila feeding behaviour and metabolism.
Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Functionalization ofInternational journal of molecular sciences · 2026Article
- Reserpine prolongs lifespan but compromises locomotion and heat-stress resilience in Drosophila melanogaster.npj aging · 2026Article
- Feeding state-dependent neuropeptidergic modulation of reciprocally interconnected inhibitory neurons biases sensorimotor decisions in Drosophila.Nature communications · 2025Article
- Rpl12 is a conserved ribophagy receptor.Nature cell biology · 2025Article
- Serotonergic modulation of swallowing in a complete fly vagus nerve connectome.Current biology : CB · 2024Article
- Activation of the 5-HT1A Receptor by Eltoprazine Restores Mitochondrial and Motor Deficits in aInternational journal of molecular sciences · 2024Article
- Serotonergic amplification of odor-evoked neural responses maps onto flexible behavioral outcomes.eLife · 2024Article
- An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Review
- Article
- Serotonergic control of feeding microstructure inFrontiers in behavioral neuroscience · 2022Article
- Assessing the cognitive status of Drosophila by the value-based feeding decision.NPJ aging and mechanisms of disease · 2021Article
- Feeding, hunger, satiety and serotonin in invertebrates.Proceedings. Biological sciences · 2020Article
- Structural Differences in the Digestive Tract Between Females and Males Could Modulate Regurgitation Behavior in Anastrepha ludens (Diptera: Tephritidae).Journal of insect science (Online) · 2019Article
- Using Drosophila behavioral assays to characterize terebrid venom-peptide bioactivity.Scientific reports · 2018Article
- Satiation state-dependent dopaminergic control of foraging in Drosophila.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals have evolved to maintain homeostasis in a changing external environment by adapting their internal metabolism and feeding behaviour. Metabolism and behaviour are coordinated by neuromodulation; a number of the implicated neuromodulatory systems are homologous between mammals and the vinegar fly, an important neurogenetic model. We investigated whether silencing fly neuromodulatory networks would elicit coordinated changes in feeding, behavioural activity and metabolism. We employed transgenic lines that allowed us to inhibit broad cellular sets of the dopaminergic, serotonergic, octopaminergic, tyraminergic and neuropeptide F systems. The genetically-manipulated animals were assessed for changes in their overt behavioural responses and metabolism by monitoring eleven parameters: activity; climbing ability; individual feeding; group feeding; food discovery; both fed and starved respiration; fed and starved lipid content; and fed/starved body weight. The results from these 55 experiments indicate that individual neuromodulatory system effects on feeding behaviour, motor activity and metabolism are dissociated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.