Evidence map›Paper›PMID 28821763›Full record

ArticleScientific reports2017

Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase.

Roberto Benoni, Christina M Beck, Fernando Garza-Sánchez, Stefano Bettati, Andrea Mozzarelli, Christopher S Hayes, Barbara Campanini

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Serine Acetyltransferase fromInternational journal of molecular sciences · 2026
    Article
  2. iScience · 2026
    Article
  3. Structure-Functional Examination of Cysteine Synthase A (CysK) fromInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Roberto BenoniDipartimento di Medicina e Chirurgia, Università di Parma, Parma, Italy.
Christina M BeckDepartment of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, USA.
Fernando Garza-SánchezDepartment of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, USA.
Stefano BettatiDipartimento di Medicina e Chirurgia, Università di Parma, Parma, Italy.ORCID 0000-0001-6787-0594
Andrea MozzarelliIstituto Nazionale Biostrutture e Biosistemi, Rome, Italy.
Christopher S HayesDepartment of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, USA. chayes@lifesci.ucsb.edu.
Barbara CampaniniDipartimento di Scienze degli Alimenti e del Farmaco, Università di Parma, Parma, Italy. barbara.campanini@unipr.it.ORCID 0000-0003-0359-0627
University of Parma · ITUniversity of California, Santa Barbara · US

Funding

Molecular mechanisms of antibacterial CDI toxin activationR01GM117373 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOULDING, CELIA, HAYES, CHRISTOPHER S. · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM117373
6 · The paper itself

Abstract

Contact-dependent growth inhibition (CDI) is a wide-spread mechanism of inter-bacterial competition. CDI

Indexed as

Bacterial ToxinsCysteine SynthaseModels, BiologicalProtein BindingProtein MultimerizationSerine O-AcetyltransferaseBacterial ToxinsCysteine SynthaseSerine O-Acetyltransferase

Identifiers

PMID28821763
PMCPMC5562914
OpenAlexW2746444668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.