Evidence map›Paper›PMID 28821654›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Wnt9a Can Influence Cell Fates and Neural Connectivity across the Radial Axis of the Developing Cochlea.

Vidhya Munnamalai, Ulrike J Sienknecht, R Keith Duncan, M Katie Scott, Ankita Thawani, Kristen N Fantetti, Nadia M Atallah, Deborah J Biesemeier, Kuhn H Song, Kirsten Luethy and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  11. The acquisition of positional information across the radial axis of the cochlea.Developmental dynamics : an official publication of the American Association of Anatomists · 2020
    Review
  12. Article
  13. Article
  14. Review
  15. WNT9A and WNT9B in Development and Disease.Differentiation; research in biological diversity
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Vidhya MunnamalaiDepartment of Biological Sciences.ORCID 0000-0002-4985-8265
Ulrike J SienknechtDepartment of Neuroscience and.ORCID 0000-0001-5212-2737
R Keith DuncanKresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan 48109.
M Katie ScottDepartment of Biological Sciences.ORCID 0000-0002-8494-4839
Ankita ThawaniDepartment of Biological Sciences.ORCID 0000-0002-4964-9789
Kristen N FantettiDepartment of Biological Sciences.
Nadia M AtallahCenter for Cancer Research, Purdue University, West Lafayette, Indiana 47907.ORCID 0000-0002-1819-7070
Deborah J BiesemeierDepartment of Biological Sciences.ORCID 0000-0002-8190-0400
Kuhn H SongDepartment of Biological Sciences.
Kirsten LuethyDepartment of Biological Sciences.
Eric TraubDepartment of Biological Sciences.
Donna M FeketeDepartment of Biological Sciences, dfekete@purdue.edu.ORCID 0000-0003-0662-0246
Integrative Medicine Institute · USPurdue University West Lafayette · USCarl von Ossietzky Universität Oldenburg · DEUniversity of Michigan · US

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Jun Wan · 1999 to 2026
$59.3M
Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI John Tesmer · 1985 to 2026
$43.4M
Scientific Synergy CoreP30DC005188 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOLAN, DAVID FRANCIS · 2002 to 2016
$10.3M
DEVELOPMENT STUDIES OF THE INNER EARR01DC002756 · NIDCD · PURDUE UNIVERSITY WEST LAFAYETTE · PI FEKETE, DONNA M · 1995 to 2019
$6.8M
Laser Scanning Confocal MicroscopeS10RR023734 · NCRR · PURDUE UNIVERSITY · PI FEKETE, DONNA M · 2010 to 2010
$500k
Molecular regulators of innervation and patterning across the developing cochleaF31DC015946 · NIDCD · PURDUE UNIVERSITY · PI SCOTT, MARY K · 2016 to 2017
$88k
NCI NIH HHS P30 CA023168NCI NIH HHS P30 CA082709NCRR NIH HHS S10 RR023734NIDCD NIH HHS F31 DC015946NIDCD NIH HHS P30 DC005188NIDCD NIH HHS R01 DC002756
6 · The paper itself

Abstract

Vertebrate hearing organs manifest cellular asymmetries across the radial axis that underlie afferent versus efferent circuits between the inner ear and the brain. Therefore, understanding the molecular control of patterning across this axis has important functional implications. Radial axis patterning begins before the cells become postmitotic and is likely linked to the onset of asymmetric expression of secreted factors adjacent to the sensory primordium. This study explores one such asymmetrically expressed gene,

Indexed as

AnimalsBody PatterningChick EmbryoCochleaConnectomeGene Expression Regulation, DevelopmentalNerve NetNeuronsWnt ProteinsWNT9A protein, humanWnt Proteinsaxon guidancecochleahair cellspatterningWnt

Identifiers

PMID28821654
PMCPMC5597980
OpenAlexW2745576768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.