Evidence map›Paper›PMID 28821619›Full record

ArticleThe Journal of biological chemistry2017

Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.

Risa Burr, Diedre Ribbens, Sumana Raychaudhuri, Emerson V Stewart, Jason Ho, Peter J Espenshade

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Dsc complex and its role in Golgi quality control.Biochemical Society transactions · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Risa BurrFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.ORCID 0000-0001-6851-2932
Diedre RibbensFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Sumana RaychaudhuriFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.ORCID 0000-0002-3164-0057
Emerson V StewartFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Jason HoFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Peter J EspenshadeFrom the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 peter.espenshade@jhmi.edu.ORCID 0000-0002-6433-0178
Johns Hopkins University · US

Funding

BIOCHEMISTRY, CELLULAR AND MOLECULAR BIOLOGY PROGRAMT32GM007445 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 1985 to 2021
$24.1M
Regulation of Cellular Cholesterol HomeostasisR01HL077588 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ESPENSHADE, PETER J. · 2004 to 2022
$7.8M
NHLBI NIH HHS R01 HL077588NIGMS NIH HHS T32 GM007445
6 · The paper itself

Abstract

Sterol regulatory element-binding proteins (SREBPs) in the fission yeast

Indexed as

Adenosine TriphosphatasesBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCarrier ProteinsCell Cycle ProteinsGene DeletionGlycosylationGolgi ApparatusImmunoprecipitationPeptide FragmentsPeptide HydrolasesProtein Interaction Domains and MotifsProtein MultimerizationProtein Processing, Post-TranslationalProtein TransportRecombinant Fusion ProteinsSchizosaccharomycesAdenosine TriphosphatasesBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCarrier ProteinsCell Cycle ProteinsDsc1 E3 ligase, S pombeDSC1 protein, S pombePeptide FragmentsPeptide HydrolasesRbd2 protein, S pombeRecombinant Fusion ProteinsSchizosaccharomyces pombe ProteinsSre1 protein, S pombeSre2 protein, S pombeSterol Regulatory Element Binding Protein 1Sterol Regulatory Element Binding Protein 2Transcription FactorsUbiquitin-Protein LigasesUfd1 protein, S pombeValosin Containing ProteinATPases associated with diverse cellular activities (AAA)Cdc48E3 ubiquitin ligasehypoxiamembrane transportp97Schizosaccharomyces pombeSREBPtranscription regulationVCP

Identifiers

PMID28821619
PMCPMC5625062
OpenAlexW2748847324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.