ArticleBMC geriatrics2017
Latent class analysis of multimorbidity patterns and associated outcomes in Spanish older adults: a prospective cohort study.
Article in BMC geriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 3 syntheses or guidelines pooled it, 184 citations in OpenAlex.
- Variations in multimorbidity measurement in studies evaluating hospitalisation in older adults: a systematic review.BMC geriatrics · 2025Pooled it
- Social determinants of multimorbidity patterns: A systematic review.Frontiers in public health · 2023Pooled it
- Do replicable profiles of multimorbidity exist? Systematic review and synthesis.European journal of epidemiology · 2019Pooled it
- Cost of hospital care for the older adults according to their level of frailty. A cohort study in the Lazio region, Italy.PloS one · 2019Trial
- Associations between continuous health examinations and trajectories of comorbidity of chronic disease: Evidence from a nationwide longitudinal study of middle-aged and older adults in China.Global health research and policy · 2026Article
- Latent class analysis of multimorbidity patterns and associated factors among older adult fallers in the hospital.BMC geriatrics · 2026Article
- Examining Multimorbidity in Older Adults Living in Naturally Occurring Retirement Communities, in Ontario, Canada, Using Latent Class Analysis.Journal of the American Geriatrics Society · 2026Article
- Observational
- Lifestyle and Chronic Comorbidity in Relation to Healthy Ageing in Community-Dwelling People Aged 80 and over: Preliminary Study from a Primary Health Care Service in Southern Spain.Healthcare (Basel, Switzerland) · 2026Article
- Oral Multimorbidity Patterns and Determinants Among Chinese Older Adults: A Latent Class Analysis.Clinical interventions in aging · 2026Article
- Article
- Exploring syndemic vulnerability among adolescents living in urban cities in the Netherlands: a latent class analysis.BMJ public health · 2026Article
- Middle-age healthcare spending and utilization at the intersection of comorbidities, functional limitation, and race/ethnicity.Innovation in aging · 2026Article
- Clusters of Comorbidities in Multiple Sclerosis and Their Influence on Healthcare Resource Usage.European journal of neurology · 2025Observational
- Multimorbidity and risk of atrial fibrillation in the Lifelines cohort.European heart journal open · 2025Article
- Longitudinal Trajectories of Multimorbidity and Psychosocial Resilience Resources in Midlife and Older Adults: Findings From the Health and Retirement Study.Journal of aging and health · 2025Article
- Multimorbidity patterns and mortality in older adults: a two-cohort pooled analysis.Aging clinical and experimental research · 2025Article
- Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)-Special Interest Group in Diabetes.European geriatric medicine · 2025Review
- Association between sensory impairment and cardiometabolic multimorbidity among older Chinese adults: a cross-sectional study based on the China Health and Retirement Longitudinal Study.BMC geriatrics · 2025Article
- Electronic device usage pattern is associated with sleep disturbances in adolescents: a latent class analysis.European journal of pediatrics · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study sought to identify multimorbidity patterns and determine the association between these latent classes with several outcomes, including health, functioning, disability, quality of life and use of services, at baseline and after 3 years of follow-up.
methodsWe analyzed data from a representative Spanish cohort of 3541 non-institutionalized people aged 50 years old and over. Measures were taken at baseline and after 3 years of follow-up. Latent Class Analysis (LCA) was conducted using eleven common chronic conditions. Generalized linear models were conducted to determine the adjusted association of multimorbidity latent classes with several outcomes.
results63.8% of participants were assigned to the "healthy" class, with minimum disease, 30% were classified under the "metabolic/stroke" class and 6% were assigned to the "cardiorespiratory/mental/arthritis" class. Significant cross-sectional associations were found between membership of both multimorbidity classes and poorer memory, quality of life, greater burden and more use of services. After 3 years of follow-up, the "metabolic/stroke" class was a significant predictor of lower levels of verbal fluency while the two multimorbidity classes predicted poor quality of life, problems in independent living, higher risk of hospitalization and greater use of health services.
conclusionsCommon chronic conditions in older people cluster together in broad categories. These broad clusters are qualitatively distinct and are important predictors of several health and functioning outcomes. Future studies are needed to understand underlying mechanisms and common risk factors for patterns of multimorbidity and to propose more effective treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.