Evidence map›Paper›PMID 28820791›Full record

ArticleCornea2017

Teleophthalmic Approach for Detection of Corneal Diseases: Accuracy and Reliability.

Maria A Woodward, David C Musch, Christopher T Hood, Jonathan B Greene, Leslie M Niziol, V Swetha E Jeganathan, Paul P Lee

Open access · greenAbstract read
In one paragraph

Article in Cornea, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Portable Anterior Eye Segment Imaging System for Teleophthalmology.Translational vision science & technology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Tele-ophthalmology: Need of the hour.Indian journal of ophthalmology · 2020
    Review
  12. Could telehealth help eye care practitioners adapt contact lens services during the COVID-19 pandemic?Contact lens & anterior eye : the journal of the British Contact Lens Association · 2020
    Article
  13. Article
  14. Article
  15. Accuracy and Reliability of a Handheld, Nonmydriatic Fundus Camera for the Remote Detection of Optic Disc Edema.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2018
    Article
  16. Evaluation of corneal infections using a smartphone macro lens for synchronous telemedicine.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maria A Woodward*Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI; †Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI; and ‡Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI.
David C Musch
Christopher T Hood
Jonathan B Greene
Leslie M Niziol
V Swetha E Jeganathan
Paul P Lee
University of Michigan–Ann Arbor · US

Funding

Telemedicine For Anterior Eye DiseasesK23EY023596 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOODWARD, MARIA ANNEKE · 2013 to 2017
$1.1M
Assessing the impact of glaucoma and its treatment on the personR21EY025719 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MUSCH, DAVID C · 2015 to 2016
$426k
NEI NIH HHS K23 EY023596NEI NIH HHS R21 EY025719
6 · The paper itself

Abstract

purposeCorneal and anterior segment diseases cause most of the urgent visits to eye care professionals. We evaluated the diagnostic accuracy of detecting corneal diseases using external photographs from 2 portable cameras for telemedicine purposes.

methodsThis is a prospective study of adults with a clinical diagnosis of corneal pathology including corneal abrasions, ulcers, scars, and pterygia. A cornea specialist provided the gold standard diagnosis by slit-lamp examination. Images of both eyes were obtained using iTouch 5S and Nidek VersaCam cameras in multiple gazes and interpreted by 3 cornea specialists for the presence of pathology. Accuracy to detect disease was compared with gold standard diagnosis, stratified by the camera and grader. Reliability was evaluated with weighted kappa statistics. Graders assessed image quality on a Likert scale from 1 (poor) to 9 (optimal).

resultsA total of 198 eyes (110 subjects) were photographed. By gold standard diagnosis, 59 eyes (30%) had corneal scars, 34 (17%) had ulcers, 13 (7%) had abrasions, 10 (5%) had pterygia, and 82 (41%) were normal. Sensitivity to detect AS pathology ranged from 54% to 71% for the iTouch and 66% to 75% for the Nidek, across graders; specificity ranged from 82% to 96% for the iTouch and 91% to 98% for the Nidek. The intergrader reliability was moderate to strong (kappa ranges: 0.54-0.71 for the iTouch; 0.75-0.76 for the Nidek). Quality ratings were variable between graders.

conclusionsExternal photographs taken by standard, nonenhanced portable cameras and interpreted remotely by ophthalmologist graders yielded sensitivity values that are not yet suitable for telemedicine applications. Additional work is needed to improve the ability to detect AS pathology remotely.

Indexed as

AdolescentAdultAgedAged, 80 and overCorneal DiseasesFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedObserver VariationOphthalmologyPhotographyProspective StudiesReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID28820791
PMCPMC5646384
OpenAlexW2746039530

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.